Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 2/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9090435 | 0.80 | CES2 (0.33) | KMT2ACES2CES1ATML3MBTL1 | |
| SCHEMBL11531757 | 0.79 | KMT2A (0.35) | KMT2AATML3MBTL1KDM4EALDH1A1 | |
| SCHEMBL7510243 | 0.79 | KMT2A (0.44) | KMT2AATML3MBTL1KDM4EALDH1A1 | |
| SCHEMBL27543188 | 0.78 | KMT2A (0.34) | KMT2AATML3MBTL1KDM4EALDH1A1 | |
| SCHEMBL9090443 | 0.76 | SMN1; SMN2 (0.46) | L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL9384051 | 0.76 | DPP4 (0.39) | KMT2AATMDPP4F2 | |
| SCHEMBL8090075 | 0.76 | TSHR (0.39) | KMT2AATML3MBTL1KDM4EALDH1A1 | |
| SCHEMBL7679328 | 0.76 | KMT2A (0.41) | KMT2AATMKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9985742 | 0.74 | DPP4 (0.38) | KMT2AATMALDH1A1DPP4F2 | |
| SCHEMBL7819515 | 0.73 | HTR2A (0.39) | L3MBTL1KDM4ESLC6A2SLC6A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0829480-B1 | Tetrazolyl-substituted quinuclidines as substance P antagonists | PFIZER (US) | 2000-12-20 | — | — | EP | disclosed |
| US-5939434-A | Tetrazolyl-substituted quinuclidines as substance P antagonists | PFIZER PHARMACEUTICALS INC. (JP) | 1999-08-17 | — | — | US | disclosed |
| EP-0829480-A2 | Tetrazolyl-substituted quinuclidines as substance P antagonists | PFIZER INC. (US) | 1998-03-18 | — | — | EP | disclosed |