SCHEMBL6470854

SCHEMBL6470854

C1=CCC(C2(c3c(-c4ccccc4)ccc4c3Cc3cc(-c5ccccc5)ccc3-4)CCCCC2)=C1

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PGR P06401 6/20 0.40
TDP2 O95551 8/20 0.36
PDE7A Q13946 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7582386 1.00 PGR (0.40) PGRTDP2PDE7A
SCHEMBL7575272 0.99 PGR (0.38) PGRTDP2
SCHEMBL7571267 0.97 TDP2 (0.37) PGRTDP2
SCHEMBL7573525 0.94 TDP2 (0.39) PGRTDP2
SCHEMBL7940024 0.78
Hydrochloric Acid SCHEMBL6557767 0.77
SCHEMBL6469960 0.76 PNMT (0.35) PGR
SCHEMBL8998590 0.73 PNMT (0.35) PGR
SCHEMBL7575252 0.73
SCHEMBL7724810 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0955305-B1 Metallocene compound, and process for preparing polyolefin by using it MITSUI CHEMICALS INC (JP) 2005-10-26 EP disclosed
US-20020019504-A1 Stereospecific; low molecular weight MITSUI CHEMICALS, INC. (JP) 2002-02-14 US disclosed
US-6342568-B1 ADDITION POLYMERIZATION OF HIGHLYS STEREOSPECIFIC AND LOW MOLECULAR WEIGHT POLYOLEFINS USING CATALYST COMPRISING CYCLOPENTADIENYL-SUBSTITUTED FLUORENE COMPOUND COMPLEXED WITH GROUP IV METAL MITSUI CHEMICALS, INC. (JP) 2002-01-29 US disclosed
EP-0955305-A1 Metallocene compound, and process for preparing polyolefin by using it Mitsui Chemicals, Inc. (JP) 1999-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019504-A1 Stereospecific; low molecular weight RPLP1, RPS4Y1, POLA1 PGR 3576/4885TDP2 4852/4885PDE7A 3334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.