Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 14/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | STRADA | Q7RTN6 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6471314 | 0.77 | MAPK14 (0.47) | MAPK14MAOBPTGER1 | |
| SCHEMBL6473027 | 0.75 | MAPK14 (0.49) | MAPK14MAOBROCK2MAPK12MAPK11 | |
| SCHEMBL6470962 | 0.75 | MAOB (0.43) | MAPK14MAOBMAP2K4MAPK11NPC1 | |
| SCHEMBL13635300 | 0.73 | IDO1 (0.46) | MAPK14MAOB | |
| SCHEMBL4384779 | 0.73 | MAPK14 (0.50) | MAPK14MAOBPTGER1 | |
| SCHEMBL4379080 | 0.73 | MAPK14 (0.52) | MAPK14 | |
| SCHEMBL6473710 | 0.73 | MAPK14 (0.53) | MAPK14MAOBROCK2MAPK12MAPK11 | |
| SCHEMBL8926780 | 0.71 | MAPK14 (0.51) | MAPK14MAOBPTGER1MAPT | |
| SCHEMBL6473438 | 0.71 | MAPK14 (0.47) | MAPK14MAOBPTGER1 | |
| SCHEMBL6471836 | 0.71 | MAPK14 (0.47) | MAPK14MAOBPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |