Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 15/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4384779 | 0.84 | MAPK14 (0.50) | IDO1AGXTMAPK14MAOB | |
| SCHEMBL4379080 | 0.84 | MAPK14 (0.52) | MAPK14 | |
| SCHEMBL21685829 | 0.76 | IDO1 (0.53) | IDO1AGXTMAPK14MAOB | |
| SCHEMBL94520 | 0.73 | NSD2 (0.54) | IDO1AGXTMAPK14MAOBCYP1A1 | |
| SCHEMBL6470945 | 0.73 | MAPK14 (0.47) | MAPK14MAOB | |
| SCHEMBL23536359 | 0.72 | IDO1 (0.56) | IDO1AGXTMAPK14MAOB | |
| SCHEMBL21685600 | 0.71 | HSPB1 (0.51) | IDO1AGXTMAPK14MAOB | |
| SCHEMBL22391935 | 0.70 | HPD (0.47) | MAPK14CYP1A2 | |
| SCHEMBL13635334 | 0.70 | MAPK14 (0.47) | IDO1AGXTMAPK14MAOBCYP1A1 | |
| SCHEMBL18783705 | 0.69 | IDO1 (0.56) | IDO1AGXTMAPK14MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490064-B1 | SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE | PHARMACIA CORP (US) | 2009-11-18 | — | — | EP | disclosed |