Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 11/20 | 0.42 |
| ▸ | SGK1 | O00141 | 1/20 | 0.40 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6471156 | 0.78 | MAPK14 (0.41) | MAOBMAPK14 | |
| SCHEMBL4377468 | 0.77 | MAPK14 (0.43) | MAOBMAPK14MAPK11 | |
| SCHEMBL6473862 | 0.77 | MAPK14 (0.44) | MAOBMAPK14MAPK11 | |
| SCHEMBL6470956 | 0.77 | MAPK14 (0.44) | MAOBMAPK14RET | |
| SCHEMBL4379189 | 0.76 | MAPK14 (0.47) | MAOBMAPK14MAPK11 | |
| SCHEMBL6472105 | 0.76 | MAPK14 (0.41) | MAOBMAPK14MAPK11 | |
| SCHEMBL6470945 | 0.75 | MAPK14 (0.47) | MAOBMAPK14MAPK11MAP2K4NPC1 | |
| SCHEMBL6471273 | 0.75 | MAPK14 (0.44) | MAOBMAPK14 | |
| SCHEMBL6533063 | 0.74 | MAPK14 (0.42) | MAOBMAPK14MAPK11RET | |
| SCHEMBL6470939 | 0.73 | MAPK14 (0.41) | MAOBMAPK14MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |