Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 16/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6471522 | 0.88 | MAPK14 (0.42) | MAPK14P2RX7 | |
| SCHEMBL6472890 | 0.87 | MAPK14 (0.42) | MAPK14P2RX7 | |
| SCHEMBL6471472 | 0.87 | MAPK14 (0.43) | MAPK14 | |
| SCHEMBL6472065 | 0.86 | MAPK14 (0.41) | MAPK14P2RX7 | |
| SCHEMBL6471307 | 0.86 | MAPK14 (0.48) | MAPK14P2RX7 | |
| SCHEMBL6474622 | 0.86 | MAPK14 (0.47) | MAPK14P2RX7 | |
| Hydrochloric Acid SCHEMBL6472925 | 0.85 | MAPK14 (0.48) | MAPK14P2RX7 | |
| Hydrochloric Acid SCHEMBL6474634 | 0.85 | P2RX7 (0.41) | MAPK14P2RX7 | |
| SCHEMBL6473783 | 0.84 | MAPK14 (0.40) | MAPK14P2RX7 | |
| SCHEMBL6471970 | 0.84 | MAPK14 (0.44) | MAPK14P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | claimed |
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |