Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 9/20 | 0.46 |
| ▸ | ACHE | P22303 | 8/20 | 0.46 |
| ▸ | BCHE | P06276 | 8/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6490067 | 0.77 | ACHE (0.46) | BACE1ACHEBCHENPC1RAB9A | |
| SCHEMBL13676574 | 0.73 | ACHE (0.57) | BACE1ACHEBCHEDRD2DRD4 | |
| SCHEMBL13676573 | 0.73 | ACHE (0.57) | BACE1ACHEBCHEDRD2DRD4 | |
| SCHEMBL19680503 | 0.73 | ALDH1A1 (0.55) | BACE1ACHEBCHE | |
| SCHEMBL13005299 | 0.73 | ACHE (0.57) | BACE1ACHEBCHEDRD2DRD4 | |
| SCHEMBL19689038 | 0.73 | ALDH1A1 (0.55) | BACE1ACHEBCHE | |
| SCHEMBL23274795 | 0.73 | BCHE (0.47) | BACE1ACHEBCHENPC1RAB9A | |
| SCHEMBL23274792 | 0.73 | ACHE (0.47) | BACE1ACHEBCHENPC1RAB9A | |
| SCHEMBL6264795 | 0.72 | ACHE (0.57) | BACE1ACHEBCHEDRD2DRD4 | |
| SCHEMBL20901959 | 0.72 | ACHE (0.53) | BACE1ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005026165-A1 | QUINOLONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-03-24 | — | — | WO | disclosed |