Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.35 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL713716 | 0.87 | TSHR (0.47) | TPMTCA1CA2TP53TSHR | |
| SCHEMBL19026597 | 0.80 | MAPT (0.44) | CA1CA2GSK3BRXRARXRB | |
| SCHEMBL28338099 | 0.80 | TSHR (0.63) | TPMTCA1CA2TP53TSHR | |
| SCHEMBL13973687 | 0.79 | CES2 (0.54) | TPMTCA1CA2ITGA1 | |
| SCHEMBL83978 | 0.78 | CPT1B (0.58) | CA1CA2PTPN1CPT1BSRD5A2 | |
| SCHEMBL44226 | 0.77 | CES1 (0.52) | CA1CA2TSHRPTPN1 | |
| SCHEMBL8999129 | 0.76 | CES2 (0.54) | CA1CA2PTPN1 | |
| SCHEMBL4804681 | 0.76 | MAPT (0.52) | — | |
| SCHEMBL1124581 | 0.76 | ALDH1A1 (0.58) | GSK3BSRD5A2 | |
| SCHEMBL123450 | 0.76 | CES2 (0.54) | CA1CA2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005109041-A1 | COMPOSITIONS FOR USE IN THE MANUFACTURE OF LENSES | MEDICAL POLYMERS LIMITED (GB) | 2005-11-17 | — | — | WO | disclosed |