Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 20/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 14/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 14/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 12/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6477651 | 0.99 | OPRK1 (0.53) | OPRK1OPRM1OPRD1CYP2D6 | |
| Hydrochloric Acid SCHEMBL6472318 | 0.91 | OPRK1 (0.54) | OPRK1OPRM1OPRD1CYP2D6 | |
| Hydrochloric Acid SCHEMBL6475677 | 0.90 | OPRK1 (0.56) | OPRK1OPRM1OPRD1CYP2D6 | |
| Hydrochloric Acid SCHEMBL6475237 | 0.90 | OPRK1 (0.57) | OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL6250186 | 0.90 | OPRK1 (0.57) | OPRK1OPRM1OPRD1CYP2D6 | |
| Hydrochloric Acid SCHEMBL6533806 | 0.89 | OPRK1 (0.53) | OPRK1OPRM1OPRD1CYP2D6 | |
| Hydrochloric Acid SCHEMBL6477009 | 0.87 | OPRM1 (0.57) | OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL8701795 | 0.87 | LTB4R (0.43) | OPRK1OPRM1OPRD1CYP2D6 | |
| Hydrochloric Acid SCHEMBL6477279 | 0.86 | OPRM1 (0.40) | OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL6251224 | 0.84 | OPRK1 (0.58) | OPRK1OPRM1OPRD1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005004796-A2 | SULFONYLAMINO PHENYLACETAMIDE DERIVATIVES AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2005-01-20 | — | — | WO | claimed |