Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3406406 | 0.81 | TDP1 (0.54) | ALDH1A1POLBCYP3A4PARP1MAPT | |
| SCHEMBL29216340 | 0.80 | RAB9A (0.46) | RAB9ANPC1MYCHPGDALDH1A1 | |
| SCHEMBL6446499 | 0.79 | ERCC5 (0.41) | RAB9ANPC1HPGDKCNK3KCNK9 | |
| SCHEMBL7925207 | 0.77 | NPC1 (0.42) | RAB9ANPC1HPGDKCNK3KCNK9 | |
| SCHEMBL6548199 | 0.77 | NPC1 (0.42) | RAB9ANPC1HPGDKCNK3KCNK9 | |
| SCHEMBL9359645 | 0.77 | ERCC5 (0.46) | RAB9ANPC1MYCHPGDALDH1A1 | |
| SCHEMBL9359661 | 0.77 | ERCC5 (0.46) | RAB9ANPC1MYCHPGDALDH1A1 | |
| SCHEMBL20658848 | 0.77 | ALDH1A1 (0.51) | RAB9ANPC1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL14677024 | 0.75 | RAB9A (0.41) | RAB9ANPC1MYCHPGDALDH1A1 | |
| SCHEMBL28884331 | 0.75 | RAB9A (0.41) | RAB9ANPC1MYCHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007094-A2 | ASTHMA AND ALLERGIC INFLAMMATION MODULATORS | TULARIK INC. (US) | 2005-01-27 | — | — | WO | disclosed |