SCHEMBL6473134

SCHEMBL6473134

CCCCC/C=C\C/C=C\CCCCCCCCCCCC

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 2/20 0.70
ALDH1A1 P00352 4/20 0.65
KDM4E B2RXH2 3/20 0.65
F7 P08709 3/20 0.65
F3 P13726 3/20 0.65
PPARG P37231 3/20 0.65
PPARD Q03181 2/20 0.65
PPARA Q07869 2/20 0.65
FABP3 P05413 2/20 0.65
DUSP3 P51452 1/20 0.65
PTPN7 P35236 1/20 0.65
FFAR1 O14842 1/20 0.65
LMNA P02545 1/20 0.65
CYP3A4 P08684 1/20 0.65
CYP19A1 P11511 1/20 0.65
FABP4 P15090 1/20 0.65
HPGD P15428 1/20 0.65
ALOX15 P16050 1/20 0.65
TSHR P16473 1/20 0.65
PTGS1 P23219 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6477506 1.00 TRPV1 (0.70) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL6472470 1.00 TRPV1 (0.70) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL4750573 1.00 TRPV1 (0.70) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL220462 1.00 TRPV1 (0.70) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL20503612 1.00 TRPV1 (0.70) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL24283496 1.00 TRPV1 (0.70) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL6476959 1.00 TRPV1 (0.70) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL59342 1.00 TRPV1 (0.70) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL6477509 1.00 TRPV1 (0.70) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL18035471 1.00 TRPV1 (0.70) TRPV1ALDH1A1KDM4EF7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12403177-B2 Silk-based product formulations and methods of use COCOON BIOTECH INC. (US) 2025-09-02 US disclosed
US-11779911-B2 Production of fatty olefin derivatives via olefin metathesis PROVIVI, INC. (US) 2023-10-10 US disclosed
EP-4234522-A2 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS Provivi, Inc. (US) 2023-08-30 EP disclosed
US-20230263859-A1 SILK-BASED PRODUCT FORMULATIONS AND METHODS OF USE COCOON BIOTECH, INC. 2023-08-24 US disclosed
EP-3377465-B1 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS PROVIVI INC (US) 2023-08-02 EP disclosed
US-11633455-B2 Silk-based product formulations and methods of use COCOON BIOTECH INC. (US) 2023-04-25 US disclosed
US-20220032280-A1 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS PROVIVI, INC. (US) 2022-02-03 US disclosed
US-11077433-B2 Production of fatty olefin derivatives via olefin metathesis PROVIVI, INC. (US) 2021-08-03 US disclosed
US-20200261898-A1 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS PROVIVI, INC. (US) 2020-08-20 US disclosed
US-10596562-B2 Production of fatty olefin derivatives via olefin metathesis PROVIVI, INC. (US) 2020-03-24 US disclosed
EP-3377465-A2 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS Provivi, Inc. (US) 2018-09-26 EP disclosed
US-20180099268-A1 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS PROVIVI, INC. (US) 2018-04-12 US disclosed
US-9776179-B2 Production of fatty olefin derivatives via olefin metathesis PROVIVI, INC. (US) 2017-10-03 US disclosed
US-20170137365-A1 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS PROVIVI, INC. (US) 2017-05-18 US disclosed
WO-2005016385-A1 INSECTICIDAL AND ACARICIDAL COMPOSITIONS WITH UV BLOCKERS AND PHEROMONES SIRENE CALL PTY LTD (AU) 2005-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10596562-B2 Production of fatty olefin derivatives via olefin metathesis SREBF1, F2, SREBF2 TRPV1 3196/4885ALDH1A1 1913/4885KDM4E 4504/4885
US-20170137365-A1 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS SREBF1, F2, SREBF2 TRPV1 3196/4885ALDH1A1 1913/4885KDM4E 4504/4885
US-20200261898-A1 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS SREBF1, F2, SREBF2 TRPV1 3196/4885ALDH1A1 1913/4885KDM4E 4504/4885
US-11779911-B2 Production of fatty olefin derivatives via olefin metathesis SREBF1, F2, SREBF2 TRPV1 3196/4885ALDH1A1 1913/4885KDM4E 4504/4885
US-20180099268-A1 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS SREBF1, F2, SREBF2 TRPV1 3196/4885ALDH1A1 1913/4885KDM4E 4504/4885
US-11077433-B2 Production of fatty olefin derivatives via olefin metathesis SREBF1, F2, SREBF2 TRPV1 3196/4885ALDH1A1 1913/4885KDM4E 4504/4885
US-20220032280-A1 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS SREBF1, F2, SREBF2 TRPV1 3196/4885ALDH1A1 1913/4885KDM4E 4504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.