SCHEMBL4750573

SCHEMBL4750573

CCCCCC=CCC=CCCCCCC

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 2/20 0.70
ALDH1A1 P00352 4/20 0.65
KDM4E B2RXH2 3/20 0.65
F7 P08709 3/20 0.65
F3 P13726 3/20 0.65
PPARG P37231 3/20 0.65
PPARD Q03181 2/20 0.65
PPARA Q07869 2/20 0.65
FABP3 P05413 2/20 0.65
DUSP3 P51452 1/20 0.65
PTPN7 P35236 1/20 0.65
FFAR1 O14842 1/20 0.65
LMNA P02545 1/20 0.65
CYP3A4 P08684 1/20 0.65
CYP19A1 P11511 1/20 0.65
FABP4 P15090 1/20 0.65
HPGD P15428 1/20 0.65
ALOX15 P16050 1/20 0.65
TSHR P16473 1/20 0.65
PTGS1 P23219 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6477506 1.00 TRPV1 (0.70) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL6472470 1.00 TRPV1 (0.70) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL6473134 1.00 TRPV1 (0.70) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL220462 1.00 TRPV1 (0.70) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL20503612 1.00 TRPV1 (0.70) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL24283496 1.00 TRPV1 (0.70) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL6476959 1.00 TRPV1 (0.70) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL59342 1.00 TRPV1 (0.70) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL6477509 1.00 TRPV1 (0.70) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL18035471 1.00 TRPV1 (0.70) TRPV1ALDH1A1KDM4EF7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240018123-A1 COMPOUND FOR INHIBITING OR DISINTEGRATING ANDROGEN RECEPTOR, AND PHARMACEUTICAL USE THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2024-01-18 US disclosed
CN-109715607-B Compounds that inhibit the formation of the C-MYC/MAX/DNA complex 国立癌症中心 2022-07-12 CN disclosed
EP-3525788-A1 TREATMENT OF SYNUCLEINOPATHIES Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE) (DE) 2019-08-21 EP disclosed
CN-109846884-A With TOR kinase inhibitor for treating cancer 西格诺药品有限公司 2019-06-07 CN disclosed
CN-109715159-A Anticancer medicine composition 国立癌症中心 2019-05-03 CN disclosed
CN-105358177-B Combination therapy comprising TOR kinase inhibitor and IMID compound for treating cancer 西格诺药品有限公司 2018-11-23 CN disclosed
WO-2018069312-A1 TREATMENT OF SYNUCLEINOPATHIES DEUTSCHES ZENTRUM FÜR NEURODEGENERATIVE ERKRANKUNGEN E. V. (DZNE) (DE) 2018-04-19 WO disclosed
EP-3178816-A1 1,2,4-OXADIAZOLE BENZOIC ACID COMPOUND AND ITS USE FOR NONSENSE SUPPRESSION AND THE TREATMENT OF DISEASE PTC Therapeutics, Inc. (US) 2017-06-14 EP disclosed
EP-3103800-A1 1,2,4-OXADIAZOLE BENZOIC ACID COMPOUND AND ITS USE FOR NONSENSE SUPPRESSION AND THE TREATMENT OF DISEASE PTC Therapeutics, Inc. (US) 2016-12-14 EP disclosed
EP-2654751-B1 PHOSPHORUS-SUBSTITUTED QUINOXALINE-TYPE PIPERIDINE COMPOUNDS AND USES THEREOF PURDUE PHARMA LP (US) 2016-11-23 EP disclosed
WO-2003099221-A2 METHODS FOR USING JNK INHIBITORS FOR TREATING OR PREVENTING DISEASE-RELATED WASTING SIGNAL PHARMACEUTICALS, INC. (US) 2003-12-04 WO disclosed
US-5753704-A Therapeutic compositions comprising unsaturated dioic acids or derivatives thereof UNICHEMA CHEMIE B.V. (NL) 1998-05-19 US disclosed
EP-0662946-B1 UNSATURATED ALIPHATIC DICARBOXYLIC ACIDS UNICHEMA CHEMIE BV (NL) 1998-03-11 EP disclosed
US-5705144-A SKIN LIGHTENING COMPOSITION AND RADIATION RESISTANCE UNILEVER PATENT HOLDINGS B.V. (NL) 1998-01-06 US disclosed
EP-0662818-B1 COSMETIC COMPOSITION CONTAINING RETINOL UNILEVER PLC (GB) 1997-11-05 EP disclosed
EP-0662946-A1 UNSATURATED ALIPHATIC DICARBOXYLIC ACIDS UNICHEMA CHEMIE B.V. (NL) 1995-07-19 EP disclosed
EP-0662818-A1 COSMETIC COMPOSITION CONTAINING RETINOL UNILEVER PLC (GB) 1995-07-19 EP disclosed
WO-1994007462-A1 COSMETIC COMPOSITION CONTAINING RETINOL UNILEVER PLC (GB) 1994-04-14 WO disclosed
WO-1994007837-A1 UNSATURATED ALIPHATIC DICARBOXYLIC ACIDS UNICHEMA CHEMIE B.V. (NL) 1994-04-14 WO disclosed
WO-1991013872-A1 THERAPEUTICALLY USEFUL HETEROCYCLIC INDOLE COMPOUNDS THE UPJOHN COMPANY (US) 1991-09-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018123-A1 COMPOUND FOR INHIBITING OR DISINTEGRATING ANDROGEN RECEPTOR, AND PHARMACEUTICAL USE THEREOF AR, NR5A1, SHBG TRPV1 558/4885ALDH1A1 2825/4885KDM4E 2822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.