SCHEMBL220462

SCHEMBL220462

CCCCC/C=C\C/C=C\CCCCCCCC

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 2/20 0.70
ALDH1A1 P00352 4/20 0.65
KDM4E B2RXH2 3/20 0.65
F7 P08709 3/20 0.65
F3 P13726 3/20 0.65
PPARG P37231 3/20 0.65
PPARD Q03181 2/20 0.65
PPARA Q07869 2/20 0.65
FABP3 P05413 2/20 0.65
DUSP3 P51452 1/20 0.65
PTPN7 P35236 1/20 0.65
FFAR1 O14842 1/20 0.65
LMNA P02545 1/20 0.65
CYP3A4 P08684 1/20 0.65
CYP19A1 P11511 1/20 0.65
FABP4 P15090 1/20 0.65
HPGD P15428 1/20 0.65
ALOX15 P16050 1/20 0.65
TSHR P16473 1/20 0.65
PTGS1 P23219 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6477506 1.00 TRPV1 (0.70) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL6472470 1.00 TRPV1 (0.70) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL4750573 1.00 TRPV1 (0.70) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL6473134 1.00 TRPV1 (0.70) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL20503612 1.00 TRPV1 (0.70) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL24283496 1.00 TRPV1 (0.70) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL6476959 1.00 TRPV1 (0.70) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL59342 1.00 TRPV1 (0.70) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL6477509 1.00 TRPV1 (0.70) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL18035471 1.00 TRPV1 (0.70) TRPV1ALDH1A1KDM4EF7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3880642-B1 METHOD FOR PRODUCING FATTY ALCOHOL ESTERS OF HYDROXY CARBOXYLIC ACIDS KETOLIPIX THERAPEUTICS GMBH (DE) 2026-01-14 EP claimed
US-20260115139-A1 Amino Acid-Containing Ionizable Lipids for the Delivery of Therapeutic Agents NANOVATION THERAPEUTICS INC. (CA) 2026-04-30 US disclosed
US-20260102357-A1 Sulfur-Containing Ionizable Lipids for the Delivery of Therapeutic Agents NANOVATION THERAPEUTICS INC. (CA) 2026-04-16 US disclosed
US-20260102347-A1 Sulfur-Containing Ionizable Lipids for the Delivery of Therapeutic Agents NANOVATION THERAPEUTICS INC. (CA) 2026-04-16 US disclosed
EP-4705481-A2 CIRCULAR RNA COMPOSITIONS AND METHODS Orna Therapeutics, Inc. (US) 2026-03-11 EP disclosed
EP-4683905-A1 IONIZABLE ANIONIC LIPIDS Nanovation Therapeutics Inc. (CA) 2026-01-28 EP disclosed
EP-3880642-B1 METHOD FOR PRODUCING FATTY ALCOHOL ESTERS OF HYDROXY CARBOXYLIC ACIDS KETOLIPIX THERAPEUTICS GMBH (DE) 2026-01-14 EP disclosed
EP-4638417-A1 SULFUR-CONTAINING IONIZABLE LIPIDS FOR THE DELIVERY OF NUCLEIC ACIDS AND OTHER THERAPEUTIC AGENTS Nanovation Therapeutics Inc. (CA) 2025-10-29 EP disclosed
EP-4638465-A1 IONIZABLE LIPIDS WITH DEGRADABLE HEAD Turn Biotechnologies, Inc. (US) 2025-10-29 EP disclosed
EP-4634390-A2 CIRCULAR RNA COMPOSITIONS AND METHODS Orna Therapeutics, Inc. (US) 2025-10-22 EP disclosed
WO-2010048536-A2 PROCESSES FOR PREPARING LIPIDS ALNYLAM PHARMACEUTICALS, INC. (US) 2010-04-29 WO disclosed
WO-2009132131-A1 AMINO LIPID BASED IMPROVED LIPID FORMULATION ALNYLAM PHARMACEUTICALS, INC. (US) 2009-10-29 WO disclosed
EP-1727780-A1 PROCESS FOR PREPARING (METH)ACRYLIC ESTERS. BASF AKTIENGESELLSCHAFT (DE) 2006-12-06 EP disclosed
WO-2005082828-A1 METHOD FOR THE PRODUCTION OF (METH)ACRYLIC ACID ESTERS BASF AKTIENGESELLSCHAFT (DE) 2005-09-09 WO disclosed
US-20050100588-A1 Self-adhesive matrix plaster containing an active ingredient and based on polyurethane gels BEIERSDORF AG 2005-05-12 US disclosed
EP-0439427-B1 Aqueous emulsions containing antioxidants CIBA GEIGY AG (CH) 1995-08-30 EP disclosed
US-5116534-A AQUEOUS EMULSIONS CONTAINING ANTIOXIDANTS CIBA-GEIGY CORPORATION (US) 1992-05-26 US disclosed
EP-0439427-A1 Aqueous emulsions containing antioxidants CIBA-GEIGY AG (CH) 1991-07-31 EP disclosed
US-4440940-A HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS AMERICAN CYANAMID COMPANY (US) 1984-04-03 US disclosed
US-4230878-A AND 4-(UNSATURATED ALKYL)AMINOBENZOIC ACIDS AND DERIVATIVES AMERICAN CYANAMID COMPANY (US) 1980-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260102357-A1 Sulfur-Containing Ionizable Lipids for the Delivery of Therapeutic Agents SGMS1, SGMS2, NSUN2 TRPV1 3307/4885ALDH1A1 3109/4885KDM4E 3300/4885
US-20050100588-A1 Self-adhesive matrix plaster containing an active ingredient and based on polyurethane gels PLOD3, COL14A1, LCP1 TRPV1 1069/4885ALDH1A1 1266/4885KDM4E 1336/4885
US-20260115139-A1 Amino Acid-Containing Ionizable Lipids for the Delivery of Therapeutic Agents SLC43A1, SLC7A1, SLC7A5 TRPV1 4530/4885ALDH1A1 2734/4885KDM4E 4032/4885
US-20260102347-A1 Sulfur-Containing Ionizable Lipids for the Delivery of Therapeutic Agents NSUN2, SGMS2, SGMS1 TRPV1 3688/4885ALDH1A1 3276/4885KDM4E 3583/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.