Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28949753 | 0.92 | TSHR (0.37) | TSHRALDH1A1 | |
| SCHEMBL703176 | 0.86 | TSHR (0.32) | TSHR | |
| SCHEMBL29074805 | 0.81 | TSHR (0.36) | TSHR | |
| SCHEMBL27976456 | 0.77 | TSHR (0.38) | TSHRALDH1A1 | |
| SCHEMBL2348007 | 0.77 | — | — | |
| SCHEMBL19210228 | 0.75 | — | — | |
| SCHEMBL17017289 | 0.72 | FAAH (0.39) | TSHR | |
| SCHEMBL18092328 | 0.72 | FAAH (0.39) | TSHR | |
| SCHEMBL29259380 | 0.70 | FFAR1 (0.38) | — | |
| SCHEMBL827354 | 0.70 | TSHR (0.39) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513816-A2 | METHOD OF PREPARING A 5H-DIBENZ(B,F)AZEPINE-5-CARBOXAMIDE | TARO PHARMACEUTICALS U.S.A., INC. (US) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003106414-A2 | METHOD OF PREPARING A 5H-DIBENZ[B,F]AZEPINE-5-CARBOXAMIDE | TARO PHARMACEUTICALS U.S.A., INC. (US) | 2003-12-24 | — | — | WO | disclosed |