Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.54 |
| ▸ | PI4KA | P42356 | 3/20 | 0.54 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.54 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.54 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.45 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL9424258 | 0.93 | CYP1A2 (0.55) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL9021758 | 0.85 | ADORA2A (0.43) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL9021976 | 0.85 | ADORA2A (0.43) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL9021750 | 0.85 | ADORA2A (0.43) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL9011476 | 0.85 | NT5E (0.42) | ADORA2AADORA3ADORA1CYP1A2TSHR | |
| SCHEMBL786455 | 0.84 | ADORA2A (0.49) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL17352601 | 0.84 | ADORA2A (0.65) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL30332114 | 0.84 | ADORA2A (0.49) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL786016 | 0.83 | ADORA2A (0.50) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL2954550 | 0.83 | ADORA2A (0.66) | ADORA2API4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11986480-B2 | Heterocyclic compound | TOHOKU UNIVERSITY (JP) | 2024-05-21 | — | — | US | disclosed |
| US-20200163970-A1 | HETEROCYCLIC COMPOUND | TOHOKU UNIVERSITY (JP) | 2020-05-28 | — | — | US | disclosed |
| EP-1535923-A1 | Synthesis of acyclic nucleoside derivatives | Medivir Aktiebolag (SE) | 2005-06-01 | — | — | EP | disclosed |
| EP-1131323-A1 | SYNTHESIS OF ACYCLIC NUCLEOSIDE DERIVATIVES | Medivir Aktiebolag (SE) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000008025-A1 | SYNTHESIS OF ACYCLIC NUCLEOSIDE DERIVATIVES | MEDIVIR AB (SE) | 2000-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200163970-A1 | HETEROCYCLIC COMPOUND | SQSTM1, BECN1, ATG7 | ADORA2A 4202/4885PI4KA 578/4885PI4K2B 527/4885 |
| US-11986480-B2 | Heterocyclic compound | SQSTM1, BECN1, ATG7 | ADORA2A 4202/4885PI4KA 578/4885PI4K2B 527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.