Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.49 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.49 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.49 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.49 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.49 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.49 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.49 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.49 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.49 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.49 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.49 |
| ▸ | PSMB6 | P28072 | 2/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.49 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.49 |
| ▸ | PSMB3 | P49720 | 2/20 | 0.49 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.49 |
| ▸ | PSMA6 | P60900 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6479141 | 0.89 | MAPK1 (0.54) | YAP1MEN1KMT2APSMB11PSMA7 | |
| Hydrochloric Acid SCHEMBL6473826 | 0.88 | KMT2A (0.50) | YAP1MEN1KMT2APSMB11PSMA7 | |
| SCHEMBL6474003 | 0.88 | PSMB11 (0.47) | YAP1MEN1KMT2APSMB11PSMA7 | |
| SCHEMBL6666207 | 0.82 | CAPN1 (0.45) | YAP1PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL6472845 | 0.81 | MEN1 (0.46) | YAP1MEN1KMT2APSMB11PSMA7 | |
| SCHEMBL6473896 | 0.81 | PSMB11 (0.44) | YAP1MEN1KMT2APSMB11PSMA7 | |
| SCHEMBL6480791 | 0.80 | YAP1 (0.46) | YAP1MEN1KMT2APSMB11PSMA7 | |
| SCHEMBL6473601 | 0.79 | PSMB11 (0.44) | YAP1MEN1KMT2APSMB11PSMA7 | |
| SCHEMBL6472835 | 0.79 | CASP1 (0.51) | YAP1MEN1KMT2APSMB11PSMA7 | |
| SCHEMBL6480346 | 0.78 | PSMB11 (0.46) | PSMB11PSMA7PSMB1PSMA1PSMA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867192-B1 | Compounds useful in the treatment of inflammatory diseases | GLAXO GROUP LIMITED (GB) | 2005-03-15 | — | — | US | disclosed |
| EP-1140837-B1 | COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES | GLAXO GROUP LTD (GB) | 2004-08-18 | — | — | EP | disclosed |