Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6473874 | 1.00 | LMNA (0.41) | LMNAKMT2ATDP1PRMT5WDR77 | |
| SCHEMBL6473016 | 0.77 | POLB (0.51) | LMNAKMT2AMAPK1CYP1A2CYP3A4 | |
| SCHEMBL6473019 | 0.77 | POLB (0.51) | LMNAKMT2AMAPK1CYP1A2CYP3A4 | |
| SCHEMBL14752590 | 0.77 | FDPS (0.51) | TDP1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL14663995 | 0.77 | FDPS (0.51) | TDP1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7110057 | 0.75 | POLB (0.49) | LMNAKMT2AMAPK1CYP1A2CYP3A4 | |
| SCHEMBL30935673 | 0.74 | CHRM2 (0.46) | PRMT5WDR77CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10202643 | 0.74 | CHRM2 (0.48) | TDP1CYP1A2HTR1ADRD2CHRM1 | |
| SCHEMBL3432313 | 0.71 | CHRM2 (0.46) | TDP1CYP1A2FDPSCHRM1 | |
| SCHEMBL7552755 | 0.71 | CHRM2 (0.46) | TDP1CYP1A2CYP3A4CYP2C9CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005012209-A2 | CATALYZED ENANTIOSELECTIVE TRANSFORMATION OF ALKENES | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2005-02-10 | — | — | WO | claimed |
| WO-2005012209-A2 | CATALYZED ENANTIOSELECTIVE TRANSFORMATION OF ALKENES | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2005-02-10 | — | — | WO | disclosed |