Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9906105 | 0.98 | THRB (0.39) | THRBALDH1A1TSHRBTN3A1CYP3A4 | |
| SCHEMBL1831246 | 0.91 | THRB (0.38) | THRBALDH1A1TSHRCYP3A4CYP2D6 | |
| SCHEMBL5595272 | 0.91 | THRB (0.38) | THRBALDH1A1TSHRCYP3A4CYP2D6 | |
| SCHEMBL1831267 | 0.89 | THRB (0.39) | THRBALDH1A1TSHRCYP2D6CYP2C19 | |
| Phosphoric Acid SCHEMBL5595983 | 0.87 | THRB (0.47) | THRBALDH1A1TSHRCYP2D6CYP2C19 | |
| SCHEMBL12297123 | 0.87 | THRB (0.47) | THRBALDH1A1TSHRCYP2D6CYP2C19 | |
| SCHEMBL23894805 | 0.85 | THRB (0.48) | THRBALDH1A1TSHRCYP2D6CYP2C19 | |
| SCHEMBL17636413 | 0.82 | THRB (0.43) | THRBALDH1A1TSHRCYP2D6CYP2C19 | |
| SCHEMBL16654664 | 0.81 | THRB (0.55) | THRBALDH1A1TSHRCYP2D6CYP2C19 | |
| SCHEMBL907264 | 0.81 | ALDH1A1 (0.37) | THRBALDH1A1TSHRCYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005063778-A1 | ONE-PART SELF-ETCHING, SELF-PRIMING DENTAL ADHESIVE COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2005-07-14 | — | — | WO | disclosed |