Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.31 |
| ▸ | GSTM2 | P28161 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28078442 | 0.77 | MAPT (0.41) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL1484117 | 0.75 | MEN1 (0.66) | MEN1KMT2AMAPTL3MBTL1HTT | |
| SCHEMBL17209987 | 0.74 | PARP1 (0.35) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL31658972 | 0.74 | GSTP1 (0.46) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL3203718 | 0.74 | TDP1 (0.41) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL2313725 | 0.74 | TDP1 (0.46) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL1099537 | 0.73 | MAPT (0.50) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL30665014 | 0.72 | ALDH1A1 (0.38) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL29118433 | 0.72 | ALDH1A1 (0.38) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL6685709 | 0.71 | IDO1 (0.36) | MEN1KMT2AMAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6872573-B2 | Fluorescent creatinine assay | BAYER CORPORATION (US) | 2005-03-29 | — | — | US | claimed |
| WO-2004060832-A2 | FLUORESCENT CREATININE ASSAY | BAYER HEALTHCARE LLC (US) | 2004-07-22 | — | — | WO | claimed |
| US-20040132200-A1 | Fluorescent creatinine assay | SIEMENS HEALTHCARE DIAGNOSTICS INC. | 2004-07-08 | — | — | US | claimed |
| US-6872573-B2 | Fluorescent creatinine assay | BAYER CORPORATION (US) | 2005-03-29 | — | — | US | disclosed |
| US-6872573-B2 | Fluorescent creatinine assay | BAYER CORPORATION (US) | 2005-03-29 | — | — | US | disclosed |
| WO-2004060832-B1 | FLUORESCENT CREATININE ASSAY | BAYER HEALTHCARE LLC (US) | 2004-12-16 | — | — | WO | disclosed |
| WO-2004060832-A3 | FLUORESCENT CREATININE ASSAY | BAYER HEALTHCARE LLC (US) | 2004-10-28 | — | — | WO | disclosed |
| WO-2004060832-A2 | FLUORESCENT CREATININE ASSAY | BAYER HEALTHCARE LLC (US) | 2004-07-22 | — | — | WO | disclosed |
| WO-2004060832-A2 | FLUORESCENT CREATININE ASSAY | BAYER HEALTHCARE LLC (US) | 2004-07-22 | — | — | WO | disclosed |
| US-20040132200-A1 | Fluorescent creatinine assay | SIEMENS HEALTHCARE DIAGNOSTICS INC. | 2004-07-08 | — | — | US | disclosed |
| US-20040132200-A1 | Fluorescent creatinine assay | SIEMENS HEALTHCARE DIAGNOSTICS INC. | 2004-07-08 | — | — | US | disclosed |