Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1076589 | 0.75 | MEN1 (0.60) | MAPTALDH1A1MAPK1L3MBTL1ALDH3A1 | |
| SCHEMBL4815391 | 0.74 | MEN1 (0.40) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL6474040 | 0.73 | MEN1 (0.39) | MAPTALDH1A1MAPK1L3MBTL1ALDH3A1 | |
| SCHEMBL1100536 | 0.73 | ALDH1A1 (0.46) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL2333611 | 0.73 | TDP1 (0.41) | MAPTALDH1A1MAPK1L3MBTL1POLB | |
| SCHEMBL2310322 | 0.73 | TDP1 (0.41) | MAPTALDH1A1MAPK1L3MBTL1POLB | |
| SCHEMBL29377555 | 0.72 | ALDH1A1 (0.57) | MAPTALDH1A1MAPK1L3MBTL1ALDH3A1 | |
| SCHEMBL29374862 | 0.72 | MAPT (0.57) | MAPTALDH1A1MAPK1L3MBTL1ALDH3A1 | |
| SCHEMBL29355945 | 0.72 | ALDH1A1 (0.57) | MAPTALDH1A1MAPK1L3MBTL1ALDH3A1 | |
| SCHEMBL7066582 | 0.72 | LMNA (0.49) | MAPTALDH1A1MAPK1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8772048-B2 | Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems | KENT STATE UNIVERSITY (US) | 2014-07-08 | — | — | US | disclosed |
| US-20120190098-A1 | FLUOROGENIC COMPOUNDS CONVERTED TO FLUOROPHORES BY PHOTOCHEMICAL OR CHEMICAL MEANS AND THEIR USE IN BIOLOGICAL SYSTEMS | LELAND STANFORD JUNIOR UNIVERSITY (US) | 2012-07-26 | — | — | US | disclosed |
| US-8153446-B2 | Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems | KENT STATE UNIVERSITY (US) | 2012-04-10 | — | — | US | disclosed |
| US-20100029952-A1 | Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems | KENT STATE UNIVERSITY (US) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190098-A1 | FLUOROGENIC COMPOUNDS CONVERTED TO FLUOROPHORES BY PHOTOCHEMICAL OR CHEMICAL MEANS AND THEIR USE IN BIOLOGICAL SYSTEMS | MPI, ACR, PFAS | MAPT 2134/4885ALDH1A1 1056/4885MAPK1 2651/4885 |
| US-20100029952-A1 | Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems | MPI, ACR, PFAS | MAPT 2134/4885ALDH1A1 1056/4885MAPK1 2651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.