Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6475416 | 0.92 | CES2 (0.42) | CES2CES1MAPK8TRPV1SIGMAR1 | |
| SCHEMBL6472045 | 0.84 | CES1 (0.59) | CES2CES1FNTAFNTBSMN1; SMN2 | |
| SCHEMBL6472518 | 0.82 | CES2 (0.40) | CES2CES1SIGMAR1FNTAFNTB | |
| SCHEMBL6472226 | 0.73 | CES2 (0.42) | CES2CES1SIGMAR1FNTAFNTB | |
| SCHEMBL1052818 | 0.71 | AKR1B1 (0.58) | MAPK8SIGMAR1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL17940814 | 0.70 | HDAC1 (0.55) | TRPV1CYP1A2RAB9ASMN1; SMN2 | |
| SCHEMBL3423556 | 0.69 | CTBP2 (0.44) | CES2CES1CYP1A2CYP2C19 | |
| SCHEMBL25168667 | 0.69 | SMN1; SMN2 (0.63) | CYP1A2CYP2D6CYP2C19RAB9AFOLH1 | |
| SCHEMBL6471828 | 0.69 | CES2 (0.44) | CES2CES1LMNA | |
| SCHEMBL1137526 | 0.69 | HDAC6 (0.54) | IDO1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005109041-A1 | COMPOSITIONS FOR USE IN THE MANUFACTURE OF LENSES | MEDICAL POLYMERS LIMITED (GB) | 2005-11-17 | — | — | WO | disclosed |