Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.59 |
| ▸ | CES2 | O00748 | 2/20 | 0.59 |
| ▸ | FNTA | P49354 | 2/20 | 0.50 |
| ▸ | FNTB | P49356 | 2/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6472518 | 0.85 | CES2 (0.40) | CES1CES2FNTAFNTB | |
| SCHEMBL6474339 | 0.84 | CES2 (0.40) | CES1CES2FNTAFNTBSMN1; SMN2 | |
| SCHEMBL27619986 | 0.79 | CES1 (0.63) | CES1CES2FNTAFNTBAKR1B1 | |
| SCHEMBL4641942 | 0.78 | CES1 (0.68) | CES1CES2FNTAFNTBAKR1B1 | |
| SCHEMBL4666437 | 0.78 | HDAC1 (0.64) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL114130 | 0.78 | HDAC1 (0.64) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL8991876 | 0.78 | MEN1 (0.49) | CES1CES2AKR1B1HDAC3MEN1 | |
| SCHEMBL41907 | 0.77 | CES1 (0.58) | CES1CES2FNTAFNTBAKR1B1 | |
| SCHEMBL574185 | 0.77 | CES1 (1.00) | CES1CES2FNTAFNTBAKR1B1 | |
| SCHEMBL443150 | 0.77 | MAPT (0.63) | CES1HDAC8HDAC6HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005109041-A1 | COMPOSITIONS FOR USE IN THE MANUFACTURE OF LENSES | MEDICAL POLYMERS LIMITED (GB) | 2005-11-17 | — | — | WO | disclosed |