SCHEMBL1137526

SCHEMBL1137526

C=C(CCCc1cccc(O)c1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 2/20 0.54
MGLL Q99685 1/20 0.48
DRD2 P14416 1/20 0.47
DRD1 P21728 1/20 0.47
TAAR1 Q96RJ0 1/20 0.47
IDO1 P14902 1/20 0.47
CTBP2 P56545 1/20 0.46
OPRK1 P41145 1/20 0.46
HTR7 P34969 2/20 0.45
HDAC3 O15379 1/20 0.44
MAPK1 P28482 1/20 0.44
ADRA1A P35348 1/20 0.44
HDAC4 P56524 1/20 0.44
SLC6A3 Q01959 1/20 0.44
HDAC1 Q13547 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1137422 0.90 DRD2 (0.50) HDAC6MGLLDRD2DRD1TAAR1
SCHEMBL31170733 0.86 HDAC6 (0.52) HDAC6MGLLDRD2DRD1TAAR1
SCHEMBL17940814 0.85 HDAC1 (0.55) HDAC6HDAC3MAPK1ADRA1AHDAC4
SCHEMBL3717612 0.83 HDAC6 (0.66) HDAC6MGLLDRD2DRD1TAAR1
SCHEMBL114130 0.83 HDAC1 (0.64) HDAC6HDAC3MAPK1ADRA1AHDAC4
SCHEMBL4666437 0.83 HDAC1 (0.64) HDAC6HDAC3MAPK1ADRA1AHDAC4
SCHEMBL445493 0.83 HDAC1 (0.47) HDAC6HDAC3MAPK1ADRA1AHDAC4
SCHEMBL19656181 0.83 TAAR1 (0.46) HDAC6TAAR1HDAC3MAPK1ADRA1A
SCHEMBL679742 0.83 NPC1 (0.52) HDAC6TAAR1CTBP2HDAC3MAPK1
SCHEMBL440625 0.83 PLAAT3 (0.57) TAAR1CTBP2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1038668-B1 Photosensitive composition and planographic printing plate precursor using same FUJI PHOTO FILM CO LTD (JP) 2005-05-25 EP claimed
EP-0914964-B1 Positive type photosensitive composition for infrared lasers FUJI PHOTO FILM CO LTD (JP) 2004-12-29 EP claimed
EP-1120246-B2 Method of plate-making a planographic printing plate FUJIFILM CORP (JP) 2016-09-07 EP disclosed
EP-2042310-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2016-08-17 EP disclosed
EP-2641738-B1 Planographic printing plate precursor and method for producing a planographic printing plate FUJIFILM CORP (JP) 2016-01-20 EP disclosed
EP-2080616-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2013-11-27 EP disclosed
EP-2106907-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2013-10-16 EP disclosed
EP-2641738-A2 Method of producing planographic printing plate and planographic printing plate Fujifilm Corporation (JP) 2013-09-25 EP disclosed
EP-1162063-B1 Planographic printing plate and light-sensitive image-forming composition comprising a recurring xylenol unit-containing novolac resin. FUJIFILM CORP (JP) 2011-08-10 EP disclosed
EP-1902840-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2011-07-06 EP disclosed
EP-2042308-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2011-02-23 EP disclosed
EP-1273439-A2 Presensitized plate for use in making lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2003-01-08 EP disclosed
EP-1270258-A1 SUPPORTING BODY FOR LITHOGRAPHY BLOCK AND ORIGINAL LITHOGRAPHY BLOCK FUJI PHOTO FILM CO., LTD. (JP) 2003-01-02 EP disclosed
US-6451497-B1 DIAZO COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 2002-09-17 US disclosed
US-20020094490-A1 An aluminum plate is subjected to graining, alkali etching and anodizing, a photosensitive layer becomes alkali-soluble by photothermal conversion with laser beams FUJIFILM CORPORATION (JP) 2002-07-18 US disclosed
US-6410203-B1 WATER INSOLUBLE POLYMER AND INFRARED ABSORBER FUJI PHOTO FILM CO., LTD. (JP) 2002-06-25 US disclosed
EP-1162063-A2 Planographic printing plate precursor Fuji Photo Film Co., Ltd. (JP) 2001-12-12 EP disclosed
EP-1157854-A2 Support for lithographic printing plate and presensitized plate FUJI PHOTO FILM CO., LTD. (JP) 2001-11-28 EP disclosed
EP-1120246-A2 Planographic printing original plate and method of plate-making a planographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2001-08-01 EP disclosed
EP-1053999-A2 Positive photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 2000-11-22 EP disclosed