Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6475260 | 0.85 | CA12 (0.49) | KDM4EMAPTCA12CA1CA2 | |
| SCHEMBL6472603 | 0.79 | KDM4E (0.40) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL4977924 | 0.74 | CA12 (0.49) | KDM4EGAAMAPTCA12CA1 | |
| SCHEMBL68014 | 0.74 | ALDH1A1 (0.57) | KDM4EGAAL3MBTL1MAPTCA12 | |
| SCHEMBL6471350 | 0.72 | CA12 (0.47) | KDM4EGAAL3MBTL1MAPTCA12 | |
| Hydrochloric Acid SCHEMBL4352471 | 0.72 | ALDH1A1 (0.56) | KDM4EGAAL3MBTL1MAPTCA12 | |
| SCHEMBL3558703 | 0.72 | MYC (0.58) | KDM4EGAAL3MBTL1ALDH1A1TTR | |
| SCHEMBL14950602 | 0.70 | ALDH1A1 (0.54) | KDM4EGAAL3MBTL1MAPTCA12 | |
| SCHEMBL14950582 | 0.70 | ALDH1A1 (0.54) | KDM4EGAAL3MBTL1MAPTCA12 | |
| SCHEMBL6471904 | 0.69 | CA12 (0.47) | KDM4EGAAL3MBTL1MAPTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |