Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | CYP2A13 | Q16696 | 2/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28808559 | 0.87 | ALDH1A1 (0.64) | ALDH1A1KDM4ECYP2A13FAAHMEN1 | |
| SCHEMBL20036088 | 0.83 | ALDH1A1 (0.57) | ALDH1A1KDM4EPOLBCYP2A13FAAH | |
| SCHEMBL2107499 | 0.77 | ALDH1A1 (0.96) | ALDH1A1KDM4EPOLBCYP2A13MEN1 | |
| SCHEMBL18753626 | 0.76 | KDM4E (0.70) | ALDH1A1KDM4EPOLBCYP2A13RAB9A | |
| SCHEMBL29941203 | 0.76 | ALDH1A1 (1.00) | ALDH1A1KDM4EPOLBCYP2A13RAB9A | |
| SCHEMBL29087431 | 0.76 | KDM4E (0.64) | ALDH1A1KDM4EPOLBCYP2A13MEN1 | |
| SCHEMBL4036908 | 0.75 | ALDH1A1 (0.68) | ALDH1A1KDM4EPOLBCYP2A13MEN1 | |
| SCHEMBL17962428 | 0.74 | KDM4E (0.72) | ALDH1A1KDM4EPOLBCYP2A13MEN1 | |
| SCHEMBL3222136 | 0.74 | ALDH1A1 (0.66) | ALDH1A1KDM4EFAAHMEN1KMT2A | |
| SCHEMBL30965800 | 0.74 | DRD2 (0.58) | HTR1AHTR2AHTR7HTR6DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916812-B2 | Dietetic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-07-12 | — | — | US | disclosed |
| US-20030232807-A1 | Alpha-aminoamide derivatives as melanocortin agonists | POINDEXTER GRAHAM S (US) | 2003-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232807-A1 | Alpha-aminoamide derivatives as melanocortin agonists | MC1R, MC5R, MC4R | ALDH1A1 2808/4885KDM4E 2608/4885POLB 3800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.