Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10675913 | 0.85 | ALDH1A1 (0.49) | KDM4EALDH1A1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL9309478 | 0.85 | ALDH1A1 (0.49) | KDM4EALDH1A1KMT2APOLBMEN1 | |
| SCHEMBL8026458 | 0.83 | GABRA2 (0.54) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10913942 | 0.82 | KMT2A (0.46) | KDM4EALDH1A1KMT2APOLBMEN1 | |
| SCHEMBL10848533 | 0.82 | GABRA2 (0.53) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9310026 | 0.81 | ALDH1A1 (0.47) | KDM4EALDH1A1KMT2APOLBMEN1 | |
| SCHEMBL9311365 | 0.81 | ALDH1A1 (0.47) | KDM4EALDH1A1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL9526287 | 0.80 | KMT2A (0.47) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL838436 | 0.80 | KMT2A (0.44) | KDM4EALDH1A1KMT2APOLBMEN1 | |
| SCHEMBL6949643 | 0.79 | KMT2A (0.43) | KDM4EALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050209251-A1 | Substituted pyrazolo-pyrimidine-4-ones | BAYER CROPSCIENCE AG (DE) | 2005-09-22 | — | — | US | disclosed |
| EP-0846113-B1 | 1-(PYRIDYL)-PYRAZOLS AND THEIR USE AS HERBICIDES | BASF AG (DE) | 2003-01-29 | — | — | EP | disclosed |
| US-6107253-A | GOOD HERBICIDAL ACTION AND ARE TOLERABLE IN CROPS SUCH AS WHEAT OR RICE | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-22 | — | — | US | disclosed |
| WO-1997007114-A1 | 1-(PYRIDYL)-PYRAZOLS AND THEIR USE AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1997-02-27 | — | — | WO | disclosed |
| US-5262382-A | Preemergent or postemengent herbicides | FMC CORPORATION (US) | 1993-11-16 | — | — | US | disclosed |
| US-5250504-A | Pre- and postemergence | FMC CORPORATION (US) | 1993-10-05 | — | — | US | disclosed |
| US-5198014-A | Herbicidal beta-pyrazolylacrylic acid compound | FMC CORPORATION (US) | 1993-03-30 | — | — | US | disclosed |
| US-5167691-A | Pre- and postemergence | FMC CORPORATION (US) | 1992-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209251-A1 | Substituted pyrazolo-pyrimidine-4-ones | P2RX4, DHFR, DDT | KDM4E 948/4885ALDH1A1 307/4885KMT2A 1779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.