SCHEMBL6475298

SCHEMBL6475298

O=P(O)(O)OOc1ccccc1F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 2/20 0.39
INPP5B P32019 1/20 0.39
INPP5A Q14642 1/20 0.39
LMNA P02545 4/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
HPGD P15428 2/20 0.39
SRC P12931 2/20 0.39
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 1/20 0.39
USP2 O75604 1/20 0.39
PDE3A Q14432 1/20 0.39
HSD17B10 Q99714 1/20 0.39
PARP10 Q53GL7 1/20 0.39
CXCL8 P10145 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
NPC1 O15118 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6474607 0.83 LMNA (0.41) LMNACYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL4430897 0.79 INPPL1 (0.57) INPPL1INPP5BINPP5ALMNACYP1A2
SCHEMBL28777742 0.76 SMN1; SMN2 (0.50) INPPL1INPP5BINPP5ALMNAHPGD
SCHEMBL29137787 0.76 CA1 (0.52) INPPL1INPP5BINPP5ALMNASRC
SCHEMBL14860951 0.76 ALDH1A1 (0.43) INPPL1INPP5BINPP5ALMNACYP1A2
SCHEMBL4946775 0.73 LMNA (0.47) INPPL1INPP5BINPP5ALMNACYP1A2
SCHEMBL10849952 0.73 ALDH1A1 (0.46) INPPL1INPP5BINPP5AHPGDALDH1A1
SCHEMBL18631959 0.72 LMNA (0.50) INPPL1INPP5BINPP5ALMNACYP1A2
SCHEMBL8519276 0.72 LMNA (0.46) INPPL1INPP5BINPP5ALMNACYP1A2
SCHEMBL29128787 0.72 L3MBTL1 (0.51) CYP1A2CYP2D6CYP2C19ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6846542-B1 UV treatment for improving performance of lubricated thin film recording media and media obtained thereby SEAGATE TECHNOLOGY LLC (US) 2005-01-25 US disclosed