Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TPH1 | P17752 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 9/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6483494 | 0.84 | RECQL (0.45) | RECQLTPH1PDE4APDE4BPDE4D | |
| SCHEMBL6775035 | 0.80 | TPH1 (0.47) | RECQLTPH1PDE4APDE4BPDE4D | |
| SCHEMBL6774108 | 0.80 | RECQL (0.45) | RECQLTPH1PDE4APDE4BPDE4D | |
| SCHEMBL69444 | 0.78 | PDE4D (0.60) | RECQLTPH1PDE4APDE4BPDE4D | |
| SCHEMBL307931 | 0.77 | TPH1 (0.49) | RECQLTPH1PDE4APDE4BPDE4D | |
| SCHEMBL6771601 | 0.76 | PDE4A (0.44) | RECQLPDE4APDE4BPDE4DPDE4C | |
| SCHEMBL1157608 | 0.76 | POLB (0.50) | RECQLPDE4APDE4BPDE4DPDE4C | |
| SCHEMBL309631 | 0.75 | TPH1 (0.51) | RECQLTPH1PDE4APDE4BPDE4D | |
| SCHEMBL8485825 | 0.73 | RECQL (0.48) | RECQLTPH1PDE4APDE4BPDE4D | |
| SCHEMBL13317191 | 0.73 | RECQL (0.61) | RECQLPDE4APDE4BPDE4DPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6919455-B2 | Purine derivative dihydrate, drugs containing the same as the active ingredient and intermediate in the production thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 2005-07-19 | — | — | US | disclosed |
| US-20040077665-A1 | Purine derivative dihydrate, drugs containing the same as the active ingredient and intermediate in the production thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 2004-04-22 | — | — | US | disclosed |
| US-6660745-B1 | Phosphodiesterase inhibitors; treatment of asthma, chronic obstructive pulmonary disease, inflammatory disorders | MITSUBISHI CHEMICAL CORPORATION (JP) | 2003-12-09 | — | — | US | disclosed |
| EP-1178046-B1 | PURINE DERIVATIVE DIHYDRATE, DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT AND INTERMEDIATE IN THE PRODUCTION THEREOF | MITSUBISHI CHEM CORP (JP) | 2003-11-19 | — | — | EP | disclosed |
| EP-1178046-A1 | PURINE DERIVATIVE DIHYDRATE, DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT AND INTERMEDIATE IN THE PRODUCTION THEREOF | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-02-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077665-A1 | Purine derivative dihydrate, drugs containing the same as the active ingredient and intermediate in the production thereof | DPYD, NUDT1, PNP | RECQL 672/4885TPH1 2215/4885PDE4A 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.