Adipic Acid

Adipic Acid

SCHEMBL647717

Cc1cccc(C(N)N)c1.O=C(O)CCCCC(=O)O

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC18A2SLC6A2SLC6A3

The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACP3 P15309 1/20 0.44
TSHR P16473 1/20 0.43
FFAR1 O14842 1/20 0.41
CYP26A1 O43174 1/20 0.40
HDAC1 Q13547 3/20 0.40
HDAC3 O15379 2/20 0.40
HDAC2 Q92769 2/20 0.40
HDAC10 Q969S8 2/20 0.40
HDAC11 Q96DB2 2/20 0.40
HDAC8 Q9BY41 2/20 0.40
HDAC6 Q9UBN7 2/20 0.40
GAA P10253 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC9 Q9UKV0 1/20 0.40
HDAC5 Q9UQL6 1/20 0.40
KIF11 P52732 3/20 0.40
SLC6A9 P48067 1/20 0.40
LTA4H P09960 1/20 0.40
PARP1 P09874 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionic Acid SCHEMBL11709487 0.87 ACP3 (0.46) ACP3CYP26A1KIF11SLC6A9PARP1
Acetic Acid SCHEMBL11703691 0.84 ACP3 (0.50) ACP3CYP26A1HDAC8HDAC6KIF11
Adipic Acid SCHEMBL15167368 0.82 TSHR (0.53) TSHRFFAR1HDAC1HDAC3HDAC2
SCHEMBL11706165 0.81 ACP3 (0.47) ACP3KIF11PARP1
Adipic Acid SCHEMBL5180701 0.81 TSHR (0.51) TSHRFFAR1HDAC1HDAC3HDAC2
Sebacic Acid SCHEMBL9311898 0.81 HDAC11 (0.52) TSHRFFAR1HDAC1HDAC3HDAC2
Adipic Acid SCHEMBL1506376 0.81 TSHR (0.51) TSHRFFAR1HDAC1HDAC3HDAC2
SCHEMBL2743434 0.81 ACP3 (0.44) ACP3TSHRFFAR1CYP26A1GAA
SCHEMBL4931341 0.81 SLC6A9 (0.45) ACP3FFAR1CYP26A1KIF11SLC6A9
SCHEMBL78261 0.80 ACHE (0.52) ACP3GAAPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2255978-B1 LAMINATE AND PNEUMATIC TIRE USING THE LAMINATE YOKOHAMA RUBBER CO LTD (JP) 2013-02-27 EP claimed
US-20110011507-A1 LAMINATE AND PNEUMATIC TIRE USING THE LAMINATE THE YOKOHAMA RUBBER CO., LTD. (JP) 2011-01-20 US claimed
EP-2255978-A1 LAMINATE AND PNEUMATIC TIRE USING THE LAMINATE The Yokohama Rubber Co., Ltd. (JP) 2010-12-01 EP claimed
US-7052628-B2 Transition metal carboxylates as catalysts for oxygen scavenging CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2006-05-30 US claimed
WO-2005056721-A1 TRANSITION METAL CARBOXYLATES AS CATALYSTS FOR OXYGEN SCAVENGING CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2005-06-23 WO claimed
US-20050104033-A1 Transition metal carboxylates as catalysts for oxygen scavenging CRYOVAC, INC. 2005-05-19 US claimed
EP-0918818-B1 MULTI-COMPONENT OXYGEN SCAVENGING COMPOSITION CHEVRON PHILLIPS CHEMICAL CO (US) 2002-02-27 EP claimed
EP-0809447-B1 MULTI-COMPONENT OXYGEN SCAVENGER SYSTEM USEFUL IN FILM PACKAGING CHEVRON CHEM CO (US) 2001-01-03 EP claimed
EP-0918818-A1 MULTI-COMPONENT OXYGEN SCAVENGING COMPOSITION Chevron Chemical Company LLC (US) 1999-06-02 EP claimed
US-5776361-A Multi-component oxygen scavenging composition CHEVRON CHEMICAL COMPANY (US) 1998-07-07 US claimed
US-5744246-A Oxygen scavenging ribbons and articles employing the same CHEVRON CHEMICAL COMPANY (US) 1998-04-28 US claimed
WO-1998006779-A1 MULTI-COMPONENT OXYGEN SCAVENGING COMPOSITION CHEVRON CHEMICAL COMPANY LLC (US) 1998-02-19 WO claimed
EP-0809447-A1 MULTI-COMPONENT OXYGEN SCAVENGER SYSTEM USEFUL IN FILM PACKAGING CHEVRON CHEMICAL COMPANY (US) 1997-12-03 EP claimed
US-5660761-A OXYGEN SCAVENGING LAYER COMPRISED OF OXIDIZABLE COMPOUND, SECOND, SEPARATE LAYER COMPRISED OF OXIDATION CATALYST CHEVRON CHEMICAL COMPANY (US) 1997-08-26 US claimed
WO-1996025058-A1 MULTI-COMPONENT OXYGEN SCAVENGER SYSTEM USEFUL IN FILM PACKAGING CHEVRON CHEMICAL COMPANY (US) 1996-08-22 WO claimed
US-11283043-B2 Laminated film and process for manufacturing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-03-22 US disclosed
US-11038145-B2 Laminated film and process for manufacturing the same, as well as method for analyzing laminated film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-06-15 US disclosed
EP-0691202-A1 LAMINATE, LAMINATED FILM AND MOLDING SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-01-10 EP disclosed
EP-0691376-A1 RESIN COMPOSITION, LAMINATE, AND LAMINATED FILM SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-01-10 EP disclosed
EP-0590263-A2 Gas barrier resin composition and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-04-06 EP disclosed