SCHEMBL6477498

SCHEMBL6477498

CCOC(=O)C(CC(=O)O)N(N)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.37
MEN1 O00255 1/20 0.35
NPC1 O15118 1/20 0.35
KMT2A Q03164 1/20 0.35
ALDH1A1 P00352 5/20 0.34
LMNA P02545 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PIN1 Q13526 1/20 0.33
CYP2D6 P10635 2/20 0.32
EGLN1 Q9GZT9 1/20 0.32
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
SOAT1 P35610 1/20 0.32
CAD P27708 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6476025 0.98 ALOX15 (0.35) ALOX15MEN1NPC1KMT2AALDH1A1
SCHEMBL3257425 0.76 MGAM (0.40) ALOX15MEN1NPC1KMT2AALDH1A1
SCHEMBL3311455 0.74 ALDH1A1 (0.43) ALOX15MEN1NPC1KMT2AALDH1A1
SCHEMBL27450027 0.74 ALDH1A1 (0.35) ALOX15MEN1NPC1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL3248744 0.74 MGAM (0.39) ALOX15ALDH1A1LMNAHSD17B10PIN1
Hydrochloric Acid SCHEMBL7497803 0.73 TDP1 (0.40) MEN1KMT2ALMNACYP2D6SMN1; SMN2
SCHEMBL1074666 0.71 ALOX15 (0.42) ALOX15MEN1NPC1KMT2AALDH1A1
SCHEMBL1074665 0.71 ALOX15 (0.42) ALOX15MEN1NPC1KMT2AALDH1A1
SCHEMBL730378 0.70 ALDH1A1 (0.32) MEN1NPC1KMT2AALDH1A1LMNA
SCHEMBL9794612 0.70 TDP1 (0.48) ALOX15MEN1NPC1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6972328-B2 Non-aggregating non-quenching oligomer comprising nucelotide analogs, method of synthesis and use thereof EPOCH BIOSCIENCES, INC. (US) 2005-12-06 US disclosed
US-20040116689-A1 Non-aggregating non-quenching oligomer comprising nucelotide analogs, method of synthesis and use thereof EPOCH BIOSCIENCES, INC. (US) 2004-06-17 US disclosed