SCHEMBL1074666

SCHEMBL1074666

CCOC(=O)[C@@H](N)CC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.42
ALDH1A1 P00352 3/20 0.40
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39
KMT2A Q03164 1/20 0.39
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
GABRP O00591 2/20 0.38
GABRD O14764 2/20 0.38
GABRA1 P14867 2/20 0.38
GABRB1 P18505 2/20 0.38
GABRG2 P18507 2/20 0.38
GABRB3 P28472 2/20 0.38
GABRA5 P31644 2/20 0.38
GABRA3 P34903 2/20 0.38
GABRA2 P47869 2/20 0.38
GABRB2 P47870 2/20 0.38
GABRA4 P48169 2/20 0.38
GABRE P78334 2/20 0.38
GABRA6 Q16445 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1074665 1.00 ALOX15 (0.42) ALOX15ALDH1A1MEN1NPC1KMT2A
Hydrochloric Acid SCHEMBL4100969 0.98 ALOX15 (0.41) ALOX15ALDH1A1MEN1NPC1KMT2A
Hydrochloric Acid SCHEMBL9076573 0.98 ALOX15 (0.41) ALOX15ALDH1A1MEN1NPC1KMT2A
SCHEMBL16098107 0.84 NOD1 (0.43) ALDH1A1NOD1
SCHEMBL14016339 0.83 ALOX15 (0.48) ALOX15ALDH1A1LMNAHSD17B10GRIK1
SCHEMBL1075213 0.83 HCAR2 (0.39) ALDH1A1LMNAGRIK1HCAR2NOD1
SCHEMBL28232296 0.83 ALOX15 (0.44) ALOX15ALDH1A1MEN1NPC1KMT2A
SCHEMBL1075212 0.83 HCAR2 (0.39) ALDH1A1LMNAGRIK1HCAR2NOD1
SCHEMBL1172849 0.82 MGAM (0.48) ALOX15ALDH1A1KMT2ALMNAHSD17B10
SCHEMBL2617390 0.82 MGAM (0.48) ALOX15ALDH1A1KMT2ALMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 293 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3956293-B1 PROCESS FOR PREPARING CYANOACETATES HENKEL AG & CO KGAA (DE) 2024-08-07 EP claimed
US-11905527-B2 Gel composition for culturing cells, production method thereof, method for culturing cells, and substrate for culturing cells SHIMADZU CORPORATION (JP) 2024-02-20 US claimed
US-11827584-B2 Process for preparing cyanoacetates HENKEL AG & CO. KGAA (DE) 2023-11-28 US claimed
CN-115304516-A Compounds with unconventional chromophores, their preparation and use 四川大学 2022-11-08 CN claimed
CN-114984296-A Thermally induced hydrogel embolic agent with X-ray developing capability and application thereof 复旦大学 2022-09-02 CN claimed
CN-113292456-B Preparation method of N-fluorenylmethoxycarbonyl-L-aspartic acid-4-tert-butyl ester 常州吉恩药业有限公司 2022-04-29 CN claimed
CN-104937041-B Method for preparing self-dispersing pigment 纳幕尔杜邦公司 2017-10-27 CN claimed
CN-104919008-B Method for preparing the silica containing self-dispersing pigment of bag 纳幕尔杜邦公司 2017-07-18 CN claimed
US-5250517-A Hypotensive and cardiotonic agents; cardiac insufficiency HOFFMANN-LA ROCHE INC. (US) 1993-10-05 US claimed
CN-120040435-A Mangiferin and derivatives thereof, preparation method and medical application thereof 安徽中医药大学 2025-05-27 CN disclosed
CN-119592379-A Engine water cooling system cleaning agent and preparation method thereof 广州市优贝材料科技有限公司 2025-03-11 CN disclosed
CN-119470406-A Phthalic dicarboxaldehyde disinfectant concentration detection test paper and preparation method thereof 山东新华莎罗雅生物技术有限公司 2025-02-18 CN disclosed
US-20250035616-A1 Organoid Compositions SHIMADZU CORPORATION (JP) 2025-01-30 US disclosed
US-20240399776-A1 COLOR DEVELOPER, THERMAL RECORDING MATERIAL, AND THERMAL RECORDING LAYER COATING MATERIAL SANKO CO., LTD. (JP) 2024-12-05 US disclosed
WO-1998053051-A1 SHORT PEPTIDES WHICH SELECTIVELY MODULATE INTRACELLULAR SIGNALLING THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 1998-11-26 WO disclosed
WO-1998029419-A1 CYANOPHOSPHORUS COMPOUNDS AND THEIR PREPARATION MONSANTO COMPANY (US) 1998-07-09 WO disclosed
WO-1998029422-A1 CYANOPHOSPHONATE DERIVATIVES MONSANTO COMPANY (US) 1998-07-09 WO disclosed
US-5278148-A Hypotensive agents HOFFMANN-LA ROCHE INC. (US) 1994-01-11 US disclosed
US-5250517-A Hypotensive and cardiotonic agents; cardiac insufficiency HOFFMANN-LA ROCHE INC. (US) 1993-10-05 US disclosed
US-5140011-A Hypotensive agents HOFFMANN-LA ROCHE, INC. (US) 1992-08-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11827584-B2 Process for preparing cyanoacetates PCCA, DNPEP, ASNS ALOX15 3996/4885ALDH1A1 2035/4885MEN1 1458/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.