SCHEMBL64779

SCHEMBL64779

C=CC(=O)OCC(CC)(COC(=O)C(=C)C)COC(=O)C(=C)C

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.57
ALDH1A1 P00352 7/20 0.53
TP53 P04637 3/20 0.53
HIF1A Q16665 3/20 0.53
CYP3A4 P08684 2/20 0.53
MAPK1 P28482 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
TSHR P16473 10/20 0.41
HPGD P15428 1/20 0.41
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6473695 1.00 THRB (0.57) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL28120025 0.94 THRB (0.51) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL7198183 0.94 ALDH1A1 (0.65) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL10633722 0.94 ALDH1A1 (0.60) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL1355388 0.92 ALDH1A1 (0.62) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL5708444 0.91 ALDH1A1 (0.58) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL11503487 0.91 ALDH1A1 (0.58) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL10148847 0.91 ALDH1A1 (0.58) THRBALDH1A1TP53HIF1ACYP3A4
SCHEMBL28097079 0.91 THRB (0.51) THRBALDH1A1TP53HIF1ACYP3A4
Acrylic Acid Methyl Ester SCHEMBL28249216 0.90 THRB (0.50) THRBALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2491915-B1 EASILY REMOVABLE CURABLE COMPOSITION FOR DENTAL USE SUN MEDICAL CO LTD (JP) 2019-07-03 EP disclosed
US-20170301950-A1 SOLID ELECTROLYTE COMPOSITION, ELECTRODE SHEET FOR BATTERY USING THE SAME, ALL SOLID STATE SECONDARY BATTERY, AND METHOD FOR MANUFACTURING ELECTRODE SHEET FOR BATTERY AND ALL SOLID STATE SECONDARY BATTERY FUJIFILM CORPORATION (JP) 2017-10-19 US disclosed
US-20170301950-A1 SOLID ELECTROLYTE COMPOSITION, ELECTRODE SHEET FOR BATTERY USING THE SAME, ALL SOLID STATE SECONDARY BATTERY, AND METHOD FOR MANUFACTURING ELECTRODE SHEET FOR BATTERY AND ALL SOLID STATE SECONDARY BATTERY FUJIFILM CORPORATION (JP) 2017-10-19 US disclosed
US-8426488-B2 Easily removable dental curable composition SUN MEDICAL CO., LTD. (JP) 2013-04-23 US disclosed
US-8362105-B2 Dental curable composition and kit for such dental curable composition SUN MEDICAL CO., LTD. (JP) 2013-01-29 US disclosed
US-8329306-B2 Barrier laminate, gas barrier film, and device using the same FUJIFILM CORPORATION (JP) 2012-12-11 US disclosed
US-8329306-B2 Barrier laminate, gas barrier film, and device using the same FUJIFILM CORPORATION (JP) 2012-12-11 US disclosed
EP-2491915-A1 EASILY REMOVABLE CURABLE COMPOSITION FOR DENTAL USE SUN MEDICAL CO., LTD. (JP) 2012-08-29 EP disclosed
US-20120213832-A1 REMOVABLE DENTAL CURABLE COMPOSITION SUN MEDICAL CO., LTD. (JP) 2012-08-23 US disclosed
US-8129443-B2 Inorganic oxide nanoparticles having an X-ray contrast property and high transparency, a functionalized silanediol monomeric or oligomeric surface modifier, and a polymerizable compound; dental composites SUN MEDICAL CO., LTD. (JP) 2012-03-06 US disclosed
US-20110070563-A1 EASILY REMOVABLE DENTAL CURABLE COMPOSITION SUN MEDICAL CO., LTD. (JP) 2011-03-24 US disclosed
EP-2272486-A1 EASILY REMOVABLE CURABLE COMPOSITION FOR DENTAL USE SUN MEDICAL CO., LTD. (JP) 2011-01-12 EP disclosed
US-20100227178-A1 BARRIER LAMINATE, GAS BARRIER FILM, AND DEVICE USING THE SAME FUJIFILM CORPORATION (JP) 2010-09-09 US disclosed
US-20100227178-A1 BARRIER LAMINATE, GAS BARRIER FILM, AND DEVICE USING THE SAME FUJIFILM CORPORATION (JP) 2010-09-09 US disclosed
US-20090137697-A1 Dental Curable Composition and Kit for Such Dental Curable Composition SUN MEDICAL CO., LTD. (JP) 2009-05-28 US disclosed
EP-1938781-A1 DENTAL CURABLE COMPOSITION AND KIT FOR SUCH DENTAL CURABLE COMPOSITION SUN MEDICAL CO., LTD. (JP) 2008-07-02 EP disclosed
US-20050123762-A1 Polymerizable composition, cured object obtained therefrom, and composite material SUN MEDICAL CO., LTD. (JP) 2005-06-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120213832-A1 REMOVABLE DENTAL CURABLE COMPOSITION SMARCA5, SMARCA1, SMARCA2 THRB 924/4885ALDH1A1 1369/4885TP53 3956/4885
US-20090137697-A1 Dental Curable Composition and Kit for Such Dental Curable Composition SETDB1, SETD1B, SETD2 THRB 2150/4885ALDH1A1 1260/4885TP53 4156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.