Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MIF | P14174 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.43 |
| ▸ | ESR1 | P03372 | 6/20 | 0.43 |
| ▸ | ERN1 | O75460 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8011498 | 0.89 | HSD17B10 (0.50) | HSD17B1ESR2ESR1ERN1HSD17B10 | |
| SCHEMBL19153570 | 0.86 | PELI1 (0.47) | MAOBMAOAMIFCA12CA9 | |
| SCHEMBL7935346 | 0.85 | SRC (0.44) | MAOBMAOAERN1 | |
| SCHEMBL1958177 | 0.82 | XDH (0.49) | MAOBMAOAMIFCA12CA9 | |
| SCHEMBL1647333 | 0.81 | ALOX5 (0.59) | MAOBMAOAMIFCA12CA9 | |
| SCHEMBL1802222 | 0.81 | CA12 (0.49) | MAOBMAOACA12CA9ESR2 | |
| SCHEMBL19798261 | 0.81 | TRIM24 (0.56) | MAOBMAOAMIFESR2ESR1 | |
| SCHEMBL16863739 | 0.79 | ESR2 (0.41) | HSD17B1ESR2ESR1ERN1 | |
| SCHEMBL18873510 | 0.79 | GPR84 (0.42) | ESR2ESR1ERN1ACHEHSD17B10 | |
| SCHEMBL19257673 | 0.79 | ESR2 (0.47) | MAOBMAOACA12CA9HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037756-A2 | NOVEL METHODS FOR THE PREPARATION OF 4-[4-(4-METHOXYMETHOXY-4'-METHYL-BIPHENYL-2-YL)-BUT-3-ENE-(E)-1-YNYL]-BENZOIC ACID | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-04-28 | — | — | WO | claimed |
| WO-2005037756-A2 | NOVEL METHODS FOR THE PREPARATION OF 4-[4-(4-METHOXYMETHOXY-4'-METHYL-BIPHENYL-2-YL)-BUT-3-ENE-(E)-1-YNYL]-BENZOIC ACID | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-04-28 | — | — | WO | disclosed |