Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 3/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | LIPE | Q05469 | 5/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4841756 | 0.88 | CHRM4 (0.37) | GCGRCHRM4LIPEMETAP2EPHX2 | |
| SCHEMBL4844861 | 0.87 | METAP2 (0.39) | GCGRLIPEMETAP2SCN9A | |
| SCHEMBL6478087 | 0.85 | GCGR (0.36) | GCGRCHRM4LIPEEPHX2L3MBTL1 | |
| SCHEMBL4850172 | 0.85 | KDM1A (0.36) | GCGRCHRM4LIPEMETAP2EPHX2 | |
| SCHEMBL4845094 | 0.84 | LIPE (0.36) | GCGRLIPEEPHX2CCR2MCHR1 | |
| SCHEMBL4848881 | 0.83 | GCGR (0.38) | GCGRCHRM4LIPEL3MBTL1CCR2 | |
| SCHEMBL4848621 | 0.82 | METAP2 (0.39) | GCGRLIPEMETAP2EPHX2CCR2 | |
| SCHEMBL4848356 | 0.81 | METAP2 (0.37) | GCGRCHRM4LIPEMETAP2SCN9A | |
| SCHEMBL6478251 | 0.80 | LIPE (0.37) | GCGRCHRM4LIPEMETAP2EPHX2 | |
| SCHEMBL4849155 | 0.80 | SMPD3 (0.38) | GCGRLIPEMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6897225-B1 | Inhibitors of αLβ2 mediated cell adhesion | TANABE SEIYAKU CO., LTD. (JP) | 2005-05-24 | — | — | US | disclosed |