Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | LIPE | Q05469 | 4/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4848881 | 0.92 | GCGR (0.38) | GCGRMCHR1CHRM4LIPEL3MBTL1 | |
| SCHEMBL6478251 | 0.89 | LIPE (0.37) | GCGRMCHR1CHRM4LIPEEPHX2 | |
| SCHEMBL4849155 | 0.89 | SMPD3 (0.38) | GCGRLIPEKCNN3PPARDPPARA | |
| SCHEMBL4845094 | 0.89 | LIPE (0.36) | GCGRMCHR1LIPEEPHX2CCR2 | |
| SCHEMBL6477360 | 0.88 | GCGR (0.35) | GCGRLIPEEPHX2KCNN3IDH1 | |
| SCHEMBL4848580 | 0.87 | KDM1A (0.35) | GCGRMCHR1CHRM4LIPEEPHX2 | |
| SCHEMBL6478091 | 0.87 | KCNN3 (0.35) | GCGRMCHR1LIPEKCNN3IDH1 | |
| SCHEMBL6488797 | 0.87 | CCR2 (0.36) | GCGRMCHR1LIPEEPHX2L3MBTL1 | |
| SCHEMBL4845087 | 0.87 | GCGR (0.36) | GCGRLIPEPPARGPPARDPPARA | |
| SCHEMBL6479033 | 0.85 | LIPE (0.33) | GCGRMCHR1CHRM4LIPEEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6897225-B1 | Inhibitors of αLβ2 mediated cell adhesion | TANABE SEIYAKU CO., LTD. (JP) | 2005-05-24 | — | — | US | disclosed |