Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 14/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 13/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6479253 | 1.00 | ADRB3 (0.56) | ADRB3ADRB1ADRB2CYP2D6MEN1 | |
| SCHEMBL6489526 | 0.91 | ADRB1 (0.49) | ADRB3ADRB1ADRB2CYP2D6MEN1 | |
| SCHEMBL6489528 | 0.91 | ADRB1 (0.49) | ADRB3ADRB1ADRB2CYP2D6MEN1 | |
| SCHEMBL7692661 | 0.91 | MEN1 (0.47) | ADRB3ADRB1ADRB2CYP2D6MEN1 | |
| SCHEMBL6531335 | 0.90 | ADRB3 (0.52) | ADRB3ADRB1ADRB2CYP2D6MEN1 | |
| SCHEMBL6531342 | 0.90 | ADRB3 (0.52) | ADRB3ADRB1ADRB2CYP2D6MEN1 | |
| SCHEMBL6532071 | 0.89 | ADRB3 (0.59) | ADRB3ADRB1CYP2D6KMT2ACASR | |
| SCHEMBL7687852 | 0.89 | ADRB3 (0.59) | ADRB3ADRB1ADRB2KMT2ACASR | |
| SCHEMBL6533443 | 0.89 | ADRB3 (0.52) | ADRB3ADRB1ADRB2CYP2D6ALDH1A1 | |
| SCHEMBL6533448 | 0.89 | ADRB3 (0.52) | ADRB3ADRB1ADRB2CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050043358-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-02-24 | — | — | US | disclosed |
| US-20020143034-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2002-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020143034-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | ADRB1, ADRB2, ADRB3 | ADRB3 3/4885ADRB1 1/4885ADRB2 2/4885 |
| US-20050043358-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | ADRB2, ADRB1, ADRB3 | ADRB3 3/4885ADRB1 2/4885ADRB2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.