Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 12/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 12/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6489528 | 1.00 | ADRB1 (0.49) | ADRB1ADRB3ADRB2CYP2D6NR3C1 | |
| SCHEMBL6479253 | 0.91 | ADRB3 (0.56) | ADRB1ADRB3ADRB2CYP2D6CASR | |
| SCHEMBL6479255 | 0.91 | ADRB3 (0.56) | ADRB1ADRB3ADRB2CYP2D6CASR | |
| SCHEMBL6480809 | 0.86 | CASR (0.45) | ADRB1ADRB3ADRB2CYP2D6CASR | |
| SCHEMBL6532071 | 0.85 | ADRB3 (0.59) | ADRB1ADRB3CYP2D6CASRKMT2A | |
| SCHEMBL6532063 | 0.85 | ADRB3 (0.59) | ADRB1ADRB3CYP2D6CASRKMT2A | |
| SCHEMBL7687852 | 0.85 | ADRB3 (0.59) | ADRB1ADRB3ADRB2CASRKMT2A | |
| SCHEMBL7692661 | 0.84 | MEN1 (0.47) | ADRB1ADRB3ADRB2CYP2D6CASR | |
| SCHEMBL7839233 | 0.84 | ADRB1 (0.42) | ADRB1ADRB3ADRB2CYP2D6CASR | |
| SCHEMBL6531342 | 0.82 | ADRB3 (0.52) | ADRB1ADRB3ADRB2CYP2D6CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050043358-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-02-24 | — | — | US | disclosed |
| US-20020143034-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2002-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020143034-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | ADRB1, ADRB2, ADRB3 | ADRB1 1/4885ADRB3 3/4885ADRB2 2/4885 |
| US-20050043358-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | ADRB2, ADRB1, ADRB3 | ADRB1 2/4885ADRB3 3/4885ADRB2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.