Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1984909 | 0.89 | ALDH1A1 (0.56) | ALDH1A1MAPK1MEN1RAB9AKMT2A | |
| SCHEMBL978595 | 0.81 | PTGER1 (0.41) | ALDH1A1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL16617019 | 0.79 | MAPK1 (0.70) | ALDH1A1MAPK1PTGER1PTGER4PTGER3 | |
| SCHEMBL30046055 | 0.79 | MAPK1 (0.70) | ALDH1A1MAPK1PTGER1PTGER4PTGER3 | |
| SCHEMBL29934895 | 0.79 | MAPK1 (0.70) | ALDH1A1MAPK1PTGER1PTGER4PTGER3 | |
| SCHEMBL19107130 | 0.79 | MAPK1 (0.70) | ALDH1A1MAPK1PTGER1PTGER4PTGER3 | |
| SCHEMBL16050181 | 0.77 | ALDH1A1 (0.43) | ALDH1A1MAPK1MEN1KMT2ACA2 | |
| SCHEMBL30292627 | 0.76 | ALDH1A1 (0.52) | ALDH1A1MAPK1PTGER1PTGER4PTGER3 | |
| SCHEMBL954787 | 0.75 | MEN1 (0.53) | ALDH1A1MAPK1MEN1RAB9AKMT2A | |
| SCHEMBL19154057 | 0.74 | MEN1 (0.46) | ALDH1A1PTGER1PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9065062-B2 | Cross-linkable iridium complexes and organic light-emitting devices using the same | UNIVERSAL DISPLAY CORPORATION (US) | 2015-06-23 | — | — | US | disclosed |
| US-20120107989-A1 | CROSS-LINKABLE IRIDIUM COMPLEXES AND ORGANIC LIGHT-EMITTING DEVICES USING THE SAME | UNIVERSAL DISPLAY CORPORATION | 2012-05-03 | — | — | US | disclosed |
| US-8119255-B2 | First and second electrode; a first organic layer between the electrodes; the first organic layer is a non-electroluminescent, cross-linked metal complex; and a second organic layer is an emissive electroluminescent organic material | UNIVERSAL DISPLAY CORPORATION (US) | 2012-02-21 | — | — | US | disclosed |
| US-20080220265-A1 | Cross-linkable Iridium Complexes and Organic Light-Emitting Devices Using the Same | UNIVERSAL DISPLAY CORPORATION (US) | 2008-09-11 | — | — | US | disclosed |
| WO-2008073440-A2 | CROSS-LINKABLE IRIDIUM COMPLEXES AND ORGANIC LIGHT-EMITTING DEVICES USING THE SAME | UNIVERSAL DISPLAY CORPORATION (US) | 2008-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080220265-A1 | Cross-linkable Iridium Complexes and Organic Light-Emitting Devices Using the Same | MTCL3, LIG4, L1CAM | ALDH1A1 681/4885MAPK1 3499/4885PTGER1 3714/4885 |
| US-20120107989-A1 | CROSS-LINKABLE IRIDIUM COMPLEXES AND ORGANIC LIGHT-EMITTING DEVICES USING THE SAME | MTCL3, LIG4, L1CAM | ALDH1A1 681/4885MAPK1 3499/4885PTGER1 3714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.