Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CPT2 | P23786 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | BHMT | Q93088 | 3/20 | 0.34 |
| ▸ | ACLY | P53396 | 3/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6130132 | 0.74 | ALDH1A1 (0.48) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL6130129 | 0.74 | ALDH1A1 (0.48) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL5478252 | 0.72 | ADRA1A (0.46) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL6479544 | 0.71 | HMGCR (0.44) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL22965333 | 0.70 | HMGCR (0.55) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL8823183 | 0.69 | — | — | |
| SCHEMBL8581488 | 0.69 | KDM4E (0.62) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL4624372 | 0.69 | KDM4E (0.62) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL20134685 | 0.69 | HMGCR (0.52) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL28632313 | 0.67 | HMGCR (0.50) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114437052-A | Method for synthesizing statin intermediate by using continuous flow microchannel reactor | 江苏福瑞康泰药业有限公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-113599467-A | Tibetan red yeast, Tibetan medicine red yeast extract, preparation method and application | 西藏月王药诊生态藏药科技有限公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-113474373-A | Novel anti-factor XI humanized antibody with antithrombotic and anti-inflammatory effects and application thereof | 阿罗诺拉股份有限公司 | 2021-10-01 | — | — | CN | disclosed |
| CN-110484562-B | Method for improving sterol content of rice by using ginseng transcription factor | 福建农林大学 | 2020-09-25 | — | — | CN | disclosed |
| US-20050010284-A1 | Method for decreasing bioprosthetic implant failure | GREGORY KENTON W (US) | 2005-01-13 | — | — | US | disclosed |
| US-20050010284-A1 | Method for decreasing bioprosthetic implant failure | GREGORY KENTON W (US) | 2005-01-13 | — | — | US | disclosed |