Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 11/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.48 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6488677 | 0.91 | ADRB1 (0.59) | ADRB3ADRB1P2RX3ADRB2 | |
| SCHEMBL6488687 | 0.91 | ADRB1 (0.59) | ADRB3ADRB1P2RX3ADRB2 | |
| Hydrochloric Acid SCHEMBL6489617 | 0.86 | ADRB3 (0.47) | ADRB3ADRB1CASRP2RX3 | |
| Hydrochloric Acid SCHEMBL6492436 | 0.85 | ADRB3 (0.47) | ADRB3ADRB1CASRP2RX3ADRB2 | |
| Hydrochloric Acid SCHEMBL6479347 | 0.82 | ADRB3 (0.48) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6479638 | 0.79 | ADRB3 (0.49) | ADRB3ADRB1CASR | |
| SCHEMBL7689127 | 0.79 | ADRB3 (0.47) | ADRB3ADRB1CASRADRB2 | |
| Hydrochloric Acid SCHEMBL6479235 | 0.78 | ADRB1 (0.46) | ADRB3ADRB1CASR | |
| SCHEMBL6489743 | 0.78 | ADRB3 (0.46) | ADRB3ADRB1CASRSLC2A1 | |
| SCHEMBL6486794 | 0.77 | ADRB1 (0.46) | ADRB3ADRB1CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050043358-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-02-24 | — | — | US | disclosed |
| US-20020143034-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2002-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020143034-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | ADRB1, ADRB2, ADRB3 | ADRB3 3/4885ADRB1 1/4885CASR 1910/4885 |
| US-20050043358-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | ADRB2, ADRB1, ADRB3 | ADRB3 3/4885ADRB1 2/4885CASR 1137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.