Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 14/20 | 0.59 |
| ▸ | ADRB3 | P13945 | 14/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6488687 | 1.00 | ADRB1 (0.59) | ADRB1ADRB3ADRB2TDP1LMNA | |
| SCHEMBL6479640 | 0.91 | ADRB3 (0.48) | ADRB1ADRB3ADRB2P2RX3 | |
| SCHEMBL6478911 | 0.84 | ADRB3 (0.71) | ADRB1ADRB3ADRB2CYP2D6MEN1 | |
| SCHEMBL6478914 | 0.84 | ADRB3 (0.71) | ADRB1ADRB3ADRB2CYP2D6MEN1 | |
| Hydrochloric Acid SCHEMBL6479024 | 0.84 | ADRB3 (0.57) | ADRB1ADRB3ADRB2TDP1LMNA | |
| Hydrochloric Acid SCHEMBL6479020 | 0.84 | ADRB3 (0.57) | ADRB1ADRB3ADRB2TDP1LMNA | |
| Hydrochloric Acid SCHEMBL6478195 | 0.83 | ADRB3 (0.58) | ADRB1ADRB3ADRB2TDP1LMNA | |
| Hydrochloric Acid SCHEMBL6478188 | 0.83 | ADRB3 (0.58) | ADRB1ADRB3ADRB2TDP1LMNA | |
| Hydrochloric Acid SCHEMBL6492690 | 0.81 | ADRB1 (0.58) | ADRB1ADRB3KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6492687 | 0.81 | ADRB1 (0.58) | ADRB1ADRB3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050043358-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-02-24 | — | — | US | disclosed |
| US-20020143034-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2002-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020143034-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | ADRB1, ADRB2, ADRB3 | ADRB1 1/4885ADRB3 3/4885ADRB2 2/4885 |
| US-20050043358-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | ADRB2, ADRB1, ADRB3 | ADRB1 2/4885ADRB3 3/4885ADRB2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.