Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 20/20 | 0.73 |
| ▸ | PDE4A | P27815 | 16/20 | 0.73 |
| ▸ | PDE4B | Q07343 | 16/20 | 0.73 |
| ▸ | PDE4C | Q08493 | 16/20 | 0.73 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.66 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6479886 | 1.00 | PDE4D (0.73) | PDE4DPDE4APDE4BPDE4CPDE3B | |
| SCHEMBL6479884 | 1.00 | PDE4D (0.73) | PDE4DPDE4APDE4BPDE4CPDE3B | |
| SCHEMBL6529216 | 0.90 | PDE4D (0.73) | PDE4DPDE4APDE4BPDE4CPDE3B | |
| SCHEMBL6529218 | 0.90 | PDE4D (0.73) | PDE4DPDE4APDE4BPDE4CPDE3B | |
| SCHEMBL6529215 | 0.90 | PDE4D (0.73) | PDE4DPDE4APDE4BPDE4CPDE3B | |
| SCHEMBL6476551 | 0.87 | PDE4D (0.70) | PDE4DPDE4APDE4BPDE4CPDE3B | |
| SCHEMBL7146899 | 0.85 | PDE4D (0.74) | PDE4DPDE4APDE4BPDE4CPDE3B | |
| SCHEMBL7146904 | 0.85 | PDE4D (0.74) | PDE4DPDE4APDE4BPDE4CPDE3B | |
| SCHEMBL6484102 | 0.85 | PDE4D (0.68) | PDE4DPDE4APDE4BPDE4CPDE3B | |
| SCHEMBL7147508 | 0.85 | PDE4B (0.80) | PDE4DPDE4APDE4BPDE4CPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6933296-B2 | Compounds effective as β2-adrenoreceptor agonists as well as PDE4-inhibitors | ALTANA PHARMA B.V. (NL) | 2005-08-23 | — | — | US | disclosed |
| US-20030195215-A1 | Compounds effective as beta-2 adrenoreceptor agonists as well pde4-inhibitors | ALTANA PHARMA B.V. (NL) | 2003-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030195215-A1 | Compounds effective as beta-2 adrenoreceptor agonists as well pde4-inhibitors | ADRB1, ADRB2, ADRA1D | PDE4D 19/4885PDE4A 10/4885PDE4B 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.