SCHEMBL6480246

SCHEMBL6480246

CS(=O)(=O)c1ccc(C(=O)O)c(Cl)c1Cn1cnnn1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
HMOX1 P09601 1/20 0.34
TP53 P04637 1/20 0.33
CNR2 P34972 1/20 0.33
F10 P00742 1/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2C9 P11712 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MAPK1 P28482 1/20 0.33
LMNA P02545 2/20 0.33
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
CYP2C19 P33261 1/20 0.32
ATM Q13315 1/20 0.32
STAT5B P51692 1/20 0.32
KDM4E B2RXH2 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6480841 0.91 F10 (0.35) ALDH1A1HMOX1TP53CNR2F10
SCHEMBL6492719 0.87 TP53 (0.39) ALDH1A1TP53F10CYP1A2CYP2C9
SCHEMBL6492717 0.82 MAPK1 (0.41) ALDH1A1HMOX1TP53F10CYP1A2
SCHEMBL6483175 0.82 KMT2A (0.33) ALDH1A1KMT2A
SCHEMBL19091620 0.81 HTT (0.41) CNR2CYP1A2CYP2C9MEN1KMT2A
SCHEMBL6480815 0.81
SCHEMBL6480849 0.80
SCHEMBL6483486 0.79 MEN1 (0.30) CYP1A2CYP2C9MEN1KMT2A
SCHEMBL6489720 0.79 TP53 (0.35) TP53MAPK1LMNAMAPT
SCHEMBL6494865 0.79 POLB (0.33) CNR2F10CYP1A2CYP2C9LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050090398-A1 Novel tetrazole derivative useful as herbicides YANAGI AKIHIKO (JP) 2005-04-28 US disclosed
EP-1476437-A1 NOVEL TETRAZOLE DERIVATIVE USEFUL AS HERBICIDES Bayer CropScience AG (DE) 2004-11-17 EP disclosed
WO-2003066607-A1 NOVEL TETRAZOLE DERIVATIVE USEFUL AS HERBICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2003-08-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050090398-A1 Novel tetrazole derivative useful as herbicides DDT, TTI1, CYP1A1 ALDH1A1 533/4885HMOX1 3657/4885TP53 1908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.