SCHEMBL6480841

SCHEMBL6480841

CS(=O)(=O)c1ccc(C(=O)Cl)c(Cl)c1Cn1cnnn1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F10 P00742 1/20 0.35
ALDH1A1 P00352 3/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
TP53 P04637 2/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
HSD17B10 Q99714 2/20 0.32
KDM4E B2RXH2 1/20 0.32
POLB P06746 1/20 0.32
ALOX12 P18054 1/20 0.32
RECQL P46063 1/20 0.32
HBB P68871 1/20 0.32
HMOX1 P09601 1/20 0.32
CNR2 P34972 1/20 0.31
ALPG P10696 1/20 0.31
TAS2R8 Q9NYW2 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6480246 0.91 ALDH1A1 (0.34) F10ALDH1A1MEN1KMT2ATP53
SCHEMBL6492719 0.87 TP53 (0.39) F10ALDH1A1MEN1KMT2ATP53
SCHEMBL6481316 0.82 MAPK1 (0.41) F10ALDH1A1MEN1KMT2ATP53
SCHEMBL6483175 0.82 KMT2A (0.33) ALDH1A1KMT2A
SCHEMBL6480849 0.82
SCHEMBL19091418 0.81 HDAC1 (0.39) F10MEN1KMT2AMAPTHSD17B10
SCHEMBL6480815 0.81
SCHEMBL6483486 0.79 MEN1 (0.30) MEN1KMT2ACYP1A2CYP2C9
SCHEMBL6480998 0.79 TP53 (0.36) ALDH1A1MEN1KMT2ATP53MAPT
SCHEMBL19091268 0.79 HSD17B10 (0.43) ALDH1A1MEN1KMT2ATP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1642925-A Novel tetrazole derivative useful as herbicides BAYER CROPSCIENCE AG (DE) 2005-07-20 CN disclosed
US-20050090398-A1 Novel tetrazole derivative useful as herbicides YANAGI AKIHIKO (JP) 2005-04-28 US disclosed
EP-1476437-A1 NOVEL TETRAZOLE DERIVATIVE USEFUL AS HERBICIDES Bayer CropScience AG (DE) 2004-11-17 EP disclosed
WO-2003066607-A1 NOVEL TETRAZOLE DERIVATIVE USEFUL AS HERBICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2003-08-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050090398-A1 Novel tetrazole derivative useful as herbicides DDT, TTI1, CYP1A1 F10 2051/4885ALDH1A1 533/4885MEN1 2766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.