SCHEMBL6494865

SCHEMBL6494865

CS(=O)(=O)c1ccc(C(=O)O)c(Cl)c1Cn1ncnn1

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.33
CNR2 P34972 1/20 0.33
F10 P00742 1/20 0.33
LMNA P02545 2/20 0.33
MYC P01106 1/20 0.32
PTGDR2 Q9Y5Y4 1/20 0.31
ADRA1D P25100 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
MAPT P10636 1/20 0.30
CYP2C9 P11712 1/20 0.30
HPGD P15428 1/20 0.30
CYP2C19 P33261 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6481153 0.91 F10 (0.35) POLBCNR2F10ADRA1D
SCHEMBL6479658 0.87 POLB (0.34) POLBCNR2F10LMNAMAPT
SCHEMBL6481052 0.82 POLB (0.40) POLBCNR2F10MYC
SCHEMBL6492960 0.81 PTGS1 (0.31)
SCHEMBL6492930 0.80 ENPP2 (0.38) POLBLMNAMYCPTGDR2
SCHEMBL6480948 0.80
SCHEMBL6489762 0.79 POLB (0.31) POLB
SCHEMBL6482294 0.79 POLB (0.33) POLB
SCHEMBL6480246 0.79 ALDH1A1 (0.34) POLBCNR2F10LMNACYP1A2
SCHEMBL6481669 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050090398-A1 Novel tetrazole derivative useful as herbicides YANAGI AKIHIKO (JP) 2005-04-28 US disclosed
EP-1476437-A1 NOVEL TETRAZOLE DERIVATIVE USEFUL AS HERBICIDES Bayer CropScience AG (DE) 2004-11-17 EP disclosed
WO-2003066607-A1 NOVEL TETRAZOLE DERIVATIVE USEFUL AS HERBICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2003-08-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050090398-A1 Novel tetrazole derivative useful as herbicides DDT, TTI1, CYP1A1 POLB 3390/4885CNR2 2127/4885F10 2051/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.