Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.58 |
| ▸ | CTSL | P07711 | 6/20 | 0.58 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.53 |
| ▸ | CTSS | P25774 | 2/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6479130 | 0.92 | CTSK (0.55) | CTSKCTSLCAPN1CTSS | |
| SCHEMBL6481485 | 0.84 | CTSK (0.56) | CTSKCTSLCAPN1CTSS | |
| SCHEMBL7327426 | 0.83 | CAPN1 (0.78) | CTSKCTSLCAPN1CTSSCTSB | |
| SCHEMBL27809377 | 0.83 | CAPN1 (0.78) | CTSKCTSLCAPN1CTSSCTSB | |
| SCHEMBL9828791 | 0.83 | CAPN1 (0.78) | CTSKCTSLCAPN1CTSSCTSB | |
| SCHEMBL2059183 | 0.82 | ITGB3 (0.70) | ITGB3ITGA2B | |
| SCHEMBL10350043 | 0.82 | CTSK (0.75) | CTSKCTSLCAPN1CTSSCTSB | |
| SCHEMBL2256227 | 0.82 | CAPN1 (0.74) | CTSKCTSLCAPN1CTSSCTSB | |
| SCHEMBL2256235 | 0.82 | CAPN1 (0.74) | CTSKCTSLCAPN1CTSSCTSB | |
| SCHEMBL2253428 | 0.82 | CAPN1 (0.74) | CTSKCTSLCAPN1CTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867192-B1 | Compounds useful in the treatment of inflammatory diseases | GLAXO GROUP LIMITED (GB) | 2005-03-15 | — | — | US | claimed |
| EP-1140837-B1 | COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES | GLAXO GROUP LTD (GB) | 2004-08-18 | — | — | EP | claimed |
| EP-1140837-A1 | COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES | GLAXO GROUP LIMITED (GB) | 2001-10-10 | — | — | EP | claimed |
| WO-2000037444-A1 | COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES | GLAXO GROUP LIMITED (GB) | 2000-06-29 | — | — | WO | claimed |
| US-6867192-B1 | Compounds useful in the treatment of inflammatory diseases | GLAXO GROUP LIMITED (GB) | 2005-03-15 | — | — | US | disclosed |
| EP-1140837-B1 | COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES | GLAXO GROUP LTD (GB) | 2004-08-18 | — | — | EP | disclosed |
| EP-1140837-A1 | COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES | GLAXO GROUP LIMITED (GB) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037444-A1 | COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES | GLAXO GROUP LIMITED (GB) | 2000-06-29 | — | — | WO | disclosed |