Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.56 |
| ▸ | CTSL | P07711 | 5/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.54 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.53 |
| ▸ | CTSS | P25774 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6479823 | 0.93 | CTSK (0.54) | CTSKCTSLP2RX7CAPN1CTSS | |
| SCHEMBL6479130 | 0.92 | CTSK (0.55) | CTSKCTSLP2RX7CAPN1CTSS | |
| SCHEMBL6474199 | 0.89 | MAPK1 (0.56) | CTSKCTSLP2RX7CAPN1CTSS | |
| SCHEMBL6474204 | 0.89 | MAPK1 (0.56) | CTSKCTSLP2RX7CAPN1CTSS | |
| SCHEMBL6473065 | 0.87 | MAPK1 (0.52) | CTSKCTSLP2RX7CAPN1CTSS | |
| SCHEMBL2059100 | 0.86 | P2RX7 (0.59) | P2RX7 | |
| SCHEMBL10349214 | 0.85 | CTSK (0.69) | CTSKCTSLCAPN1CTSS | |
| SCHEMBL6480404 | 0.84 | CTSK (0.58) | CTSKCTSLCAPN1CTSS | |
| SCHEMBL6933303 | 0.82 | CAPN1 (0.65) | CTSKCTSLCAPN1CTSS | |
| Hydrochloric Acid SCHEMBL6691605 | 0.82 | CACNA1B (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867192-B1 | Compounds useful in the treatment of inflammatory diseases | GLAXO GROUP LIMITED (GB) | 2005-03-15 | — | — | US | disclosed |
| EP-1140837-B1 | COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES | GLAXO GROUP LTD (GB) | 2004-08-18 | — | — | EP | disclosed |