Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | BUB1 | O43683 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6494834 | 0.86 | P2RX7 (0.42) | P2RX7CCR1CCR2MAPK1BUB1 | |
| SCHEMBL6488718 | 0.86 | P2RX7 (0.42) | P2RX7CCR1CCR2MAPK1HPGD | |
| SCHEMBL6480890 | 0.85 | CCR1 (0.36) | P2RX7CCR1CCR2MAPK1HPGD | |
| SCHEMBL6479768 | 0.82 | P2RX7 (0.33) | P2RX7CCR1CCR2MAPK1BUB1 | |
| SCHEMBL6490664 | 0.78 | BUB1 (0.38) | BUB1ALDH1A1TSHRKMT2AKDM4E | |
| SCHEMBL6491667 | 0.77 | CCR1 (0.32) | P2RX7CCR1CCR2 | |
| SCHEMBL6489376 | 0.77 | TP53 (0.43) | MAPK1BUB1CYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL6489730 | 0.74 | POLB (0.39) | MAPK1BUB1HPGDALDH1A1TSHR | |
| SCHEMBL6328685 | 0.74 | BUB1 (0.39) | BUB1ALDH1A1KMT2APDE3BPDE3A | |
| SCHEMBL5182692 | 0.73 | HPGD (0.47) | HPGDALDH1A1TSHRKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050090398-A1 | Novel tetrazole derivative useful as herbicides | YANAGI AKIHIKO (JP) | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090398-A1 | Novel tetrazole derivative useful as herbicides | DDT, TTI1, CYP1A1 | P2RX7 1507/4885CCR1 1965/4885CCR2 1872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.