Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.31 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27876260 | 0.81 | KDM4E (0.39) | L3MBTL1KDM4EKDM7APHF8KDM2A | |
| SCHEMBL7622688 | 0.79 | KDM4E (0.38) | L3MBTL1KDM4ETDP1ALDH1A1LMNA | |
| SCHEMBL4915510 | 0.79 | KDM4E (0.38) | L3MBTL1KDM4E | |
| SCHEMBL7522493 | 0.79 | HDAC3 (0.50) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| Palmitic Acid SCHEMBL28160875 | 0.79 | GPR84 (0.59) | MEN1KMT2ACYP2C9TDP1ALDH1A1 | |
| SCHEMBL11063771 | 0.77 | MEN1 (0.36) | MEN1KMT2ACYP2C9MAPT | |
| SCHEMBL27891550 | 0.77 | CA12 (0.46) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL27656889 | 0.77 | KDM4E (0.37) | L3MBTL1KDM4E | |
| SCHEMBL11224794 | 0.77 | MEN1 (0.43) | KDM4EMEN1KMT2ACYP2C9TDP1 | |
| SCHEMBL28204394 | 0.75 | TSHR (0.39) | L3MBTL1KDM4EMEN1KMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102796160-A | 17ss-hsd1 and sts inhibitors | SOLVAY PHARM GMBH | 2012-11-28 | — | — | CN | claimed |
| CN-101189251-B | 17 beta-HSD 1 and STS inhibitors | SOLVAY PHARM BV | 2012-09-12 | — | — | CN | claimed |
| CN-102617389-A | Synthetic method of N, N-diethyl-3-propionylaminoaniline | ZHEJIANG RUNTU CO LTD | 2012-08-01 | — | — | CN | claimed |
| CN-101448843-B | Imidazolothiazole compounds for the treatment of disease | AMBIT BIOSCIENCES CORP | 2012-05-09 | — | — | CN | claimed |
| EP-0794827-B1 | NEW BUFFER SYSTEM FOR ELECTROPHORESIS AND USE THEREOF | AMERSHAM BIOSCIENCES AB (SE) | 2002-07-10 | — | — | EP | claimed |
| CN-1293031-A | Composition for treating hair and scalp containing dandruff removing agent and acrylic acid terpolymer | OREAL (FR) | 2001-05-02 | — | — | CN | claimed |
| CN-1292260-A | Detergent composition made from keratin material | OREAL (FR) | 2001-04-25 | — | — | CN | claimed |
| US-6090252-A | NO ARTIFICIAL EXTRA BANDS DURING ELECTROPHORETIC SEPARATION BUT SHARP AND WELL-DEFINED BANDS OF MACROMOLECULES, E.G. PROTEINS, RESULT; GEL BUFFER SOLUTION CONTAINS A BASE AND TITRATING ACID, CATHODE ONE A WEAK ACID; STORAGE STABILITY | PHARMACIA BIOTECH AB (SE) | 2000-07-18 | — | — | US | claimed |
| EP-0794827-A1 | NEW BUFFER SYSTEM FOR ELECTROPHORESIS AND USE THEREOF | Pharmacia Biotech AB (SE) | 1997-09-17 | — | — | EP | claimed |
| WO-1996016724-A1 | NEW BUFFER SYSTEM FOR ELECTROPHORESIS AND USE THEREOF | PHARMACIA BIOTECH AB (SE) | 1996-06-06 | — | — | WO | claimed |
| US-10758538-B2 | Heat shock protein binding compounds, compositions, and methods for making and using same | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2020-09-01 | — | — | US | disclosed |
| US-20190038626-A1 | HEAT SHOCK PROTEIN BINDING COMPOUNDS, COMPOSITIONS, AND METHODS FOR MAKING AND USING SAME | MEMORIAL SLOAN-KETTERING CANCER CENTER | 2019-02-07 | — | — | US | disclosed |
| US-10052325-B2 | Heat shock protein binding compounds, compositions, and methods for making and using same | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2018-08-21 | — | — | US | disclosed |
| CN-105745272-B | Aqueous emulsion surface treatment agent | 大金工业株式会社 | 2018-07-03 | — | — | CN | disclosed |
| CN-105764980-B | Surface conditioning agent | 大金工业株式会社 | 2017-08-08 | — | — | CN | disclosed |
| CN-1422143-A | Leave-in hair cosmetic compositions for enhancing volume | PROCTER & GAMBLE (US) | 2003-06-04 | — | — | CN | disclosed |
| EP-0794827-B1 | NEW BUFFER SYSTEM FOR ELECTROPHORESIS AND USE THEREOF | AMERSHAM BIOSCIENCES AB (SE) | 2002-07-10 | — | — | EP | disclosed |
| US-6090252-A | NO ARTIFICIAL EXTRA BANDS DURING ELECTROPHORETIC SEPARATION BUT SHARP AND WELL-DEFINED BANDS OF MACROMOLECULES, E.G. PROTEINS, RESULT; GEL BUFFER SOLUTION CONTAINS A BASE AND TITRATING ACID, CATHODE ONE A WEAK ACID; STORAGE STABILITY | PHARMACIA BIOTECH AB (SE) | 2000-07-18 | — | — | US | disclosed |
| EP-0794827-A1 | NEW BUFFER SYSTEM FOR ELECTROPHORESIS AND USE THEREOF | Pharmacia Biotech AB (SE) | 1997-09-17 | — | — | EP | disclosed |
| WO-1996016724-A1 | NEW BUFFER SYSTEM FOR ELECTROPHORESIS AND USE THEREOF | PHARMACIA BIOTECH AB (SE) | 1996-06-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10758538-B2 | Heat shock protein binding compounds, compositions, and methods for making and using same | HSPBP1, HSF1, HSPA2 | L3MBTL1 1584/4885KDM4E 3776/4885MEN1 2935/4885 |
| US-20190038626-A1 | HEAT SHOCK PROTEIN BINDING COMPOUNDS, COMPOSITIONS, AND METHODS FOR MAKING AND USING SAME | HSPBP1, HSF1, HSPA2 | L3MBTL1 1584/4885KDM4E 3776/4885MEN1 2935/4885 |
| US-10052325-B2 | Heat shock protein binding compounds, compositions, and methods for making and using same | HSPBP1, HSF1, HSPA2 | L3MBTL1 1584/4885KDM4E 3776/4885MEN1 2935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.