Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KRAS | P01116 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | BAX | Q07812 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | LIG1 | P18858 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22237642 | 0.92 | ALDH1A1 (0.32) | ALDH1A1MAPTDNM1SMN1; SMN2KRAS | |
| SCHEMBL21689703 | 0.92 | KDM4E (0.44) | ALDH1A1MAPTDNM1KRASTP53 | |
| SCHEMBL22269676 | 0.92 | ALDH1A1 (0.32) | ALDH1A1MAPTDNM1SMN1; SMN2KRAS | |
| SCHEMBL30645503 | 0.92 | KDM4E (0.44) | ALDH1A1MAPTDNM1KRASTP53 | |
| SCHEMBL30195085 | 0.92 | ALDH1A1 (0.32) | ALDH1A1MAPTDNM1SMN1; SMN2KRAS | |
| SCHEMBL23358443 | 0.86 | MAPKAPK2 (0.33) | ALDH1A1KDM4E | |
| SCHEMBL30194724 | 0.86 | MAPKAPK2 (0.33) | ALDH1A1KDM4E | |
| SCHEMBL13701303 | 0.86 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1KDM4EATMTSHR | |
| SCHEMBL18921870 | 0.85 | L3MBTL1 (0.38) | ALDH1A1MAPTDNM1KRASMAPK1 | |
| SCHEMBL30194709 | 0.85 | L3MBTL1 (0.38) | ALDH1A1MAPTDNM1KRASMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1628962-B1 | Iodopyrazolyl carboxanilides | BAYER IP GMBH (DE) | 2014-10-01 | — | — | EP | claimed |
| US-9065062-B2 | Cross-linkable iridium complexes and organic light-emitting devices using the same | UNIVERSAL DISPLAY CORPORATION (US) | 2015-06-23 | — | — | US | disclosed |
| US-9065062-B2 | Cross-linkable iridium complexes and organic light-emitting devices using the same | UNIVERSAL DISPLAY CORPORATION (US) | 2015-06-23 | — | — | US | disclosed |
| US-9065062-B2 | Cross-linkable iridium complexes and organic light-emitting devices using the same | UNIVERSAL DISPLAY CORPORATION (US) | 2015-06-23 | — | — | US | disclosed |
| US-8580401-B2 | Curable material and its application | ETERNAL CHEMICAL CO., LTD. (TW) | 2013-11-12 | — | — | US | disclosed |
| US-8580401-B2 | Curable material and its application | ETERNAL CHEMICAL CO., LTD. (TW) | 2013-11-12 | — | — | US | disclosed |
| US-20120193611-A1 | CURABLE MATERIAL AND ITS APPLICATION | ETERNAL MATERIALS CO., LTD. (TW) | 2012-08-02 | — | — | US | disclosed |
| US-20120193611-A1 | CURABLE MATERIAL AND ITS APPLICATION | ETERNAL MATERIALS CO., LTD. (TW) | 2012-08-02 | — | — | US | disclosed |
| US-20120107989-A1 | CROSS-LINKABLE IRIDIUM COMPLEXES AND ORGANIC LIGHT-EMITTING DEVICES USING THE SAME | UNIVERSAL DISPLAY CORPORATION | 2012-05-03 | — | — | US | disclosed |
| US-20120107989-A1 | CROSS-LINKABLE IRIDIUM COMPLEXES AND ORGANIC LIGHT-EMITTING DEVICES USING THE SAME | UNIVERSAL DISPLAY CORPORATION | 2012-05-03 | — | — | US | disclosed |
| US-8119255-B2 | First and second electrode; a first organic layer between the electrodes; the first organic layer is a non-electroluminescent, cross-linked metal complex; and a second organic layer is an emissive electroluminescent organic material | UNIVERSAL DISPLAY CORPORATION (US) | 2012-02-21 | — | — | US | disclosed |
| US-20110124698-A1 | Iodopyrazolyl Carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2011-05-26 | — | — | US | disclosed |
| US-7906656-B2 | Iodopyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2011-03-15 | — | — | US | disclosed |
| US-20100167931-A1 | HETEROCYCLICALLY SUBSTITUTED HETEROCYCLYLCARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-07-01 | — | — | US | disclosed |
| US-20100152266-A1 | Iodopyrazolyl Carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-06-17 | — | — | US | disclosed |
| US-7687531-B2 | N-(3',4'dichloro-5-fluoro-1,1'-biphenyl-2-yl)-3-iodo-1-methyl-1H-pyrazole4-carboxamide; fungicides; molds/fungi/; plants/organisms/; controlling microorganisms; microbiocides; dermatophytes; Candida; Epidermophyton; Aspergillus; Trichophyton | BAYER CROPSCIENCE AG (DE) | 2010-03-30 | — | — | US | disclosed |
| US-20080220265-A1 | Cross-linkable Iridium Complexes and Organic Light-Emitting Devices Using the Same | UNIVERSAL DISPLAY CORPORATION (US) | 2008-09-11 | — | — | US | disclosed |
| US-20080220265-A1 | Cross-linkable Iridium Complexes and Organic Light-Emitting Devices Using the Same | UNIVERSAL DISPLAY CORPORATION (US) | 2008-09-11 | — | — | US | disclosed |
| WO-2008073440-A2 | CROSS-LINKABLE IRIDIUM COMPLEXES AND ORGANIC LIGHT-EMITTING DEVICES USING THE SAME | UNIVERSAL DISPLAY CORPORATION (US) | 2008-06-19 | — | — | WO | disclosed |
| US-20070066673-A1 | Iodopyrazolyl carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124698-A1 | Iodopyrazolyl Carboxanilides | IDH2, ABL1, IDH1 | ALDH1A1 804/4885MAPT 4204/4885DNM1 2566/4885 |
| US-20100167931-A1 | HETEROCYCLICALLY SUBSTITUTED HETEROCYCLYLCARBOXYLIC ACID DERIVATIVES | HPD, HAAO, HCAR2 | ALDH1A1 475/4885MAPT 3950/4885DNM1 3009/4885 |
| US-20080220265-A1 | Cross-linkable Iridium Complexes and Organic Light-Emitting Devices Using the Same | MTCL3, LIG4, L1CAM | ALDH1A1 681/4885MAPT 374/4885DNM1 1436/4885 |
| US-20120107989-A1 | CROSS-LINKABLE IRIDIUM COMPLEXES AND ORGANIC LIGHT-EMITTING DEVICES USING THE SAME | MTCL3, LIG4, L1CAM | ALDH1A1 681/4885MAPT 374/4885DNM1 1436/4885 |
| US-20070066673-A1 | Iodopyrazolyl carboxanilides | Q6ZSR9, C1S, MRPL21 | ALDH1A1 1194/4885MAPT 2769/4885DNM1 2705/4885 |
| US-20100152266-A1 | Iodopyrazolyl Carboxanilides | IDH2, ABL1, IDH1 | ALDH1A1 804/4885MAPT 4204/4885DNM1 2566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.